Kővári Lili, Kojouharova Petia, Gaál Zsófia Anna, Czigler István
Doctoral School of Psychology, ELTE Eötvös Loránd University, Kazinczy utca 23-27, Budapest H-1075, Hungary; Institute of Psychology, ELTE Eötvös Loránd University, Kazinczy utca 23-27, Budapest H-1075, Hungary; Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest H-1117, Hungary.
Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest H-1117, Hungary.
Biol Psychol. 2024 Nov;193:108956. doi: 10.1016/j.biopsycho.2024.108956. Epub 2024 Nov 23.
Visual mismatch negativity (vMMN), the difference between the event-related potentials (ERPs) to repeated (standard) events and changing (deviant) events, can be caused either by diminished activity to the repeated ones (stimulus-specific adaptation, SSA), increased activity to the new ones, or both effects. To determine which of these effects contribute to the emergence of vMMN, we investigated the effect of repetition on visual ERPs. To this end, we measured electrical brain activity to task-irrelevant stimuli both in case of stimulus onset (continuously present objects, ON-events) and stimulus offset (frequently or infrequently disappearing parts of the objects, OFF-events). We examined ERPs to changing events ("deviants"), first and second repetitions ("standards") and to changing events preceded by one, two or three different events in non-oddball (50 % deviant frequency) sequences along with ERPs to similar deviant and standard events in oddball (12,5 % deviant frequency) sequences. The absence of exogenous N1 adaptation (i.e., adaptation of the negativity in the range of putative deviant minus standard difference) in non-oddball sequences coupled with the emergence of vMMN in oddball sequences proves that vMMN can be considered more than pure stimulus-specific adaptation effect.
视觉失匹配负波（vMMN）是指对重复（标准）事件和变化（偏差）事件的事件相关电位（ERP）之间的差异，它可能是由于对重复事件的活动减少（刺激特异性适应，SSA）、对新事件的活动增加，或者是这两种效应共同导致的。为了确定这些效应中哪些导致了vMMN的出现，我们研究了重复对视觉ERP的影响。为此，我们在刺激开始（持续呈现的物体，开事件）和刺激结束（物体频繁或不频繁消失的部分，关事件）的情况下，测量了对与任务无关刺激的脑电活动。我们检查了对变化事件（“偏差刺激”）、第一次和第二次重复（“标准刺激”）以及在非奇数次序列中由一个、两个或三个不同事件之前的变化事件的ERP，同时还检查了在奇数次序列（偏差频率为12.5%）中与类似偏差和标准事件的ERP。非奇数次序列中不存在外源性N1适应（即假定偏差减去标准差异范围内负性的适应），而奇数次序列中出现vMMN，这证明vMMN不能仅仅被视为纯粹的刺激特异性适应效应。
