术后睡眠障碍的原因、影响及术前、术中和术后的治疗策略——一篇叙述性综述

Causes and Effects of Postoperative Sleep Disorders and Treatment Strategies for Preoperative, Intraoperative, and Postoperative Settings-A Narrative Review.

作者信息

Nelson Michael J, Yu Darien A, Ha Augustine V H, Wakefield Mark R, Fang Yujiang

机构信息

Department of Microbiology, Immunology & Pathology, Des Moines University College of Osteopathic Medicine, West Des Moines, IA 50266, USA.

Department of Surgery, University of Missouri School of Medicine, Columbia, MO 65212, USA.

出版信息

Clocks Sleep. 2025 Jun 22;7(3):29. doi: 10.3390/clockssleep7030029.

Abstract

Sleep is an essential part of everyday life and disturbed sleep can produce numerous deleterious effects on the body. An especially prevalent and detrimental subset of sleep disturbances are sleep disturbances that occur in patients during the postoperative period. To better understand these disorders and how to treat them, a literature search was conducted to identify and consolidate recent advancements in this field. This narrative review discusses the structure of a typical night of sleep and the causes, effects, and treatment strategies of Postoperative Sleep Disturbances (PSDs). Factors that contribute to the development of PSDs have been identified at all stages of the surgical process, including the preoperative, intraoperative, and postoperative timepoints. Exposure to these factors can accumulate during each step and may decrease the quality of sleep postoperatively. The development of PSDs has been found to affect multiple systems throughout the body and can ultimately lead to poorer recovery times and increased postoperative mortality. As a result, multiple therapeutic approaches are being investigated for their role in reducing the prevalence of these disorders. This has revealed promising interventions throughout the surgical process, such as preoperative nerve blocks, intraoperative infusions, and postoperative behavioral interventions. However, despite these successful findings, work still needs to be completed to optimize these techniques and generalize intervention strategies.

摘要

睡眠是日常生活的重要组成部分,睡眠障碍会对身体产生诸多有害影响。术后患者出现的睡眠障碍是一类特别普遍且有害的睡眠问题。为了更好地了解这些疾病及其治疗方法,我们进行了文献检索,以识别和整合该领域的最新进展。本叙述性综述讨论了典型夜间睡眠的结构以及术后睡眠障碍(PSD)的成因、影响和治疗策略。在手术过程的所有阶段,包括术前、术中和术后时间点,都已确定了导致PSD发生的因素。在每个步骤中接触这些因素可能会累积起来,并可能降低术后的睡眠质量。已发现PSD的发生会影响全身多个系统,并最终导致恢复时间延长和术后死亡率增加。因此,正在研究多种治疗方法在降低这些疾病患病率方面的作用。这揭示了在整个手术过程中有前景的干预措施,如术前神经阻滞、术中输液和术后行为干预。然而,尽管有这些成功的发现,但仍需要开展工作来优化这些技术并推广干预策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f57/12286151/d6fab1e6b4c9/clockssleep-07-00029-g001.jpg

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