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运用视觉思维探索“关系药理学”:用于心血管预防中管理非选择性抗抑郁药的系统图谱

Visual Thinking to Explore "Relational Pharmacology": Systemic Maps for Managing Non-Selective Antidepressants in Cardiovascular Prevention.

作者信息

García-Domínguez Irene, Rodríguez-Luna Azahara, Machuca Manuel

机构信息

Departamento Ciencias de la Salud y Biomédicas, Facultad de Ciencias de la Salud, Universidad Loyola Andalucía, 41074 Sevilla, Spain.

出版信息

Pharmacy (Basel). 2025 Jun 27;13(4):91. doi: 10.3390/pharmacy13040091.

Abstract

Relational pharmacology introduces an innovative approach using visual thinking to understand how drugs interact with multiple body systems, addressing the limitations of the traditional "reductionist approach". While conventional pharmacology focuses on individual drug effects, it struggles with the complexities of polypharmacy, where multiple medications interact via shared metabolic pathways. This article highlights integrating systemic maps into educational methodologies to empower students in identifying and assessing medication risks. By visualizing the body and drug therapy as interconnected systems, students can better understand complex pharmacological interactions beyond linear frameworks. This approach enables active learning and real-life case analysis, such as cardiovascular prevention with non-selective antidepressants, where multiple drug interactions must be considered. It also fosters global health education by promoting the exchange of effective teaching practices and addressing challenges in healthcare training. Systemic maps prepare students for clinical decision-making by enhancing their ability to manage risks and complex cases effectively.

摘要

关系药理学引入了一种创新方法,即运用可视化思维来理解药物如何与多个身体系统相互作用,解决了传统“还原论方法”的局限性。传统药理学专注于单一药物的作用,却难以应对多药联用的复杂性,在多药联用中,多种药物通过共同的代谢途径相互作用。本文强调将系统图谱整合到教育方法中,以使学生有能力识别和评估用药风险。通过将身体和药物治疗视为相互关联的系统进行可视化呈现,学生能够超越线性框架,更好地理解复杂的药理相互作用。这种方法能够促进主动学习和现实案例分析,比如使用非选择性抗抑郁药进行心血管预防时,必须考虑多种药物相互作用。它还通过促进有效教学实践的交流以及应对医疗培训中的挑战,推动全球健康教育。系统图谱通过提高学生有效管理风险和处理复杂病例的能力,为临床决策做好准备。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2598/12286204/c6ee792ae5b0/pharmacy-13-00091-g001.jpg

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