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Treatment of Severe Asthma Is Not "Cookie-Cutter" Medicine.

作者信息

Busse William W, Viswanathan Ravi

机构信息

Division of Allergy, Pulmonary and Critical Care Medicine University of Wisconsin School of Medicine and Public Health Madison, Wisconsin.

出版信息

Am J Respir Crit Care Med. 2025 Sep;211(9):1537-1539. doi: 10.1164/rccm.202506-1403ED.

DOI:10.1164/rccm.202506-1403ED
PMID:40700732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12432398/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a0f/12432398/d3d53bd6d6a4/rccm.202506-1403EDf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a0f/12432398/d3d53bd6d6a4/rccm.202506-1403EDf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a0f/12432398/d3d53bd6d6a4/rccm.202506-1403EDf1.jpg

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[A case of chrome asthma induced by exposure to the stone cutter dust].[一例因接触石匠粉尘诱发的铬哮喘病例]
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From standardization to personalized medicine: Moving beyond cookie-cutter treatment of esophageal cancer.从标准化到个性化医疗：超越食管癌的千篇一律治疗模式。
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Cookie cutter doesn't cut it.千篇一律的方法行不通。
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Development of gluten-free cookie using composite flour from corn and lentil flours: Study by response surface methodology.使用玉米粉和扁豆粉复合粉制作无麸质饼干的研究：响应面法研究
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Cookie-cutter management.千篇一律的管理方式
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本文引用的文献

1
Clinical Remission by a Comprehensive Severe Asthma Management Strategy Guided by Airway Inflammometry and Bioimaging.由气道炎症测定法和生物成像引导的综合重症哮喘管理策略实现临床缓解
Am J Respir Crit Care Med. 2025 Sep;211(9):1622-1635. doi: 10.1164/rccm.202412-2438OC.
2
Effect of dupilumab on exhaled nitric oxide, mucus plugs, and functional respiratory imaging in patients with type 2 asthma (VESTIGE): a randomised, double-blind, placebo-controlled, phase 4 trial.度普利尤单抗对2型哮喘患者呼出气一氧化氮、黏液栓及功能性呼吸成像的影响（VESTIGE）：一项随机、双盲、安慰剂对照的4期试验
Lancet Respir Med. 2025 Mar;13(3):208-220. doi: 10.1016/S2213-2600(24)00362-X. Epub 2025 Feb 10.
3
Stop the Asthma Treatment Elevator, We Need to Get Off!
停下哮喘治疗的电梯，我们要下去！
Am J Respir Crit Care Med. 2025 Jan 21;211(5):698-9. doi: 10.1164/rccm.202412-2431VP.
4
Clinical remission attainment, definitions, and correlates among patients with severe asthma treated with biologics: a systematic review and meta-analysis.生物制剂治疗的重度哮喘患者的临床缓解达成情况、定义及相关因素：一项系统评价和荟萃分析
Lancet Respir Med. 2025 Jan;13(1):23-34. doi: 10.1016/S2213-2600(24)00293-5. Epub 2024 Nov 14.
5
Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial.美泊利珠单抗治疗美国易恶化型嗜酸性粒细胞性哮喘城市儿童（MUPPITS-2）：一项随机、双盲、安慰剂对照、平行分组试验。
Lancet. 2022 Aug 13;400(10351):502-511. doi: 10.1016/S0140-6736(22)01198-9.
6
Predicting the benefits of type-2 targeted anti-inflammatory treatment with the prototype Oxford Asthma Attack Risk Scale (ORACLE).使用原型牛津哮喘发作风险量表（ORACLE）预测2型靶向抗炎治疗的益处。
ERJ Open Res. 2021 Feb 7;8(1). doi: 10.1183/23120541.00570-2021. eCollection 2022 Jan.
7
Biologic Therapies for Severe Asthma.重度哮喘的生物疗法
N Engl J Med. 2022 Jan 13;386(2):157-171. doi: 10.1056/NEJMra2032506.
8
Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena.在伴有气道自身免疫现象的重度嗜酸性粒细胞性哮喘患者中，对抗白细胞介素-5单克隆抗体治疗反应欠佳。
Eur Respir J. 2020 Oct 8;56(4). doi: 10.1183/13993003.00117-2020. Print 2020 Oct.
9
Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma.贝那鲁肽在重症哮喘中的糖皮质激素节省作用。
N Engl J Med. 2017 Jun 22;376(25):2448-2458. doi: 10.1056/NEJMoa1703501. Epub 2017 May 22.
10
Effects of an anti-TSLP antibody on allergen-induced asthmatic responses.抗 TSLP 抗体对变应原诱导的哮喘反应的影响。
N Engl J Med. 2014 May 29;370(22):2102-10. doi: 10.1056/NEJMoa1402895. Epub 2014 May 20.