一项使用瑞典交互式阈值算法标准的新型24-2C算法的前瞻性研究。

A Prospective Study of a New 24-2C Algorithm Using the Swedish Interactive Thresholding Algorithm Standard.

作者信息

Nishijima Euido, Noro Takahiko, Sano Kei, Ogawa Shumpei, Sumi Shunsuke, Igari Yuka, Watanabe Tomoyuki, Kishimoto Nanami, Okude Sachiyo, Lee Gary C, Iwase Aiko, Nakano Tadashi

机构信息

Department of Ophthalmology, The Jikei University School of Medicine, Nishi-shimbashi, Tokyo, Japan.

Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

出版信息

Ophthalmol Glaucoma. 2025 Jul 21. doi: 10.1016/j.ogla.2025.07.004.

DOI:10.1016/j.ogla.2025.07.004

PMID:40701407

Abstract

PURPOSE

To compare the performance of the 24-2C Swedish Interactive Thresholding Algorithm (SITA) Faster and Standard with the 10-2 SITA Standard in assessing visual function in patients with glaucoma.

DESIGN

A multicenter prospective cross-sectional study.

PARTICIPANTS

Overall, 71 eyes of 71 patients with primary open-angle or normal-tension glaucoma were included.

METHODS

The participants underwent visual field testing using the 24-2C SITA Faster, 24-2C SITA Standard (research prototype), and 10-2 SITA Standard in a randomized order on the same day. The global indices, threshold values, total deviation (TD), pattern deviation (PD), and test durations of the algorithms were compared. Correlations among the 10-2 SITA Standard mean deviation (MD) and number of depressed test point locations in the TD and PD probability plots at P < 5%, P < 2%, and P < 1% significance levels within the central 10° were analyzed.

MAIN OUTCOME MEASURES

Differences in global indices, threshold values, TD, PD, and test duration between algorithms. Correlations of the MD and number of TD and PD points of the 10-2 SITA Standard and those of the central 10° region for the 24-2C algorithms.

RESULTS

No significant differences were found in the global indices between the 24-2C SITA Faster and Standard. The 24-2C SITA Faster had a significantly shorter test duration (55.2% shorter) than the 24-2C SITA Standard. The 24-2C SITA Standard was 45.2% shorter than the combined 24-2 SITA Standard plus 10-2 SITA Standard. The 24-2C SITA Standard showed significantly higher correlation with the 10-2 SITA Standard than the 24-2C SITA Faster.

CONCLUSIONS

There were no significant differences in global indices between the 24-2C SITA Standard and 24-2C SITA Faster. However, the 24-2C SITA Standard showed a stronger correlation with the 10-2 SITA Standard. The 24-2C SITA Standard demonstrates potential for more effectively assessing central visual field function in patients with glaucoma.

FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

摘要

目的

比较24-2C瑞典交互式阈值算法（SITA）快速版和标准版与10-2 SITA标准版在评估青光眼患者视觉功能方面的性能。

设计

一项多中心前瞻性横断面研究。

参与者

共纳入71例原发性开角型或正常眼压性青光眼患者的71只眼。

方法

参与者在同一天按随机顺序接受使用24-2C SITA快速版、24-2C SITA标准版（研究原型）和10-2 SITA标准版的视野测试。比较各算法的全局指标、阈值、总偏差（TD）、模式偏差（PD）和测试时长。分析10-2 SITA标准版平均偏差（MD）与中央10°范围内P<5%、P<2%和P<1%显著性水平下TD和PD概率图中测试点压低位置数量之间的相关性。

主要观察指标

各算法之间全局指标、阈值、TD、PD和测试时长的差异。10-2 SITA标准版的MD以及24-2C算法中央10°区域的TD和PD点数之间的相关性。

结果

24-2C SITA快速版和标准版在全局指标上无显著差异。24-2C SITA快速版的测试时长显著短于24-2C SITA标准版（短55.2%）。24-2C SITA标准版比24-2 SITA标准版加10-2 SITA标准版的组合短45.2%。24-2C SITA标准版与10-2 SITA标准版的相关性显著高于24-2C SITA快速版。