Lan W H
Bull Tokyo Med Dent Univ. 1977 Jun;24(2):169-76.
In order to find a simple and effective method for endodontic treatment of recalcitrant cases, the efficacy of ammoniacal silver nitrate was re-evaluated. The modified serial tube dilution method was conducted to determine the effective antimicrobial concentration of ammoniacal silver nitrate on selected test microorganisms and clinical isolates. The effective antimicrobial concentration for the most resistant microorganism, Streptococcus faecalis, was 5.0 X 10(-10) g/ml and the effectiveness persisted for several days. The diffusion ability of 4% ammoniacal silver nitrate into the dentinal tubules from root canal wall was also tested with freshly extracted teeth treated as in routine procedure for root canal therapy. The diffusibility was evident and the extent of infiltration was various, with more infiltration at cervical dentin than at apical one.
为了找到一种用于顽固性病例根管治疗的简单有效方法,对氨硝酸银的疗效进行了重新评估。采用改良的连续试管稀释法来确定氨硝酸银对选定测试微生物和临床分离株的有效抗菌浓度。对最具耐药性的微生物粪肠球菌的有效抗菌浓度为5.0×10⁻¹⁰ g/ml,且有效性可持续数天。还使用按照根管治疗常规程序处理的新鲜拔除牙齿,测试了4%氨硝酸银从根管壁向牙本质小管的扩散能力。扩散性明显,渗透程度各不相同,颈部牙本质的渗透比根尖部更多。