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复发性急性鼻-鼻窦炎成人患者手术干预的预测因素

Predictors of Surgical Intervention in Adults With Recurrent Acute Rhinosinusitis.

作者信息

Tolaymat Obadah, Cui Ruifeng, Dewey John, Ramadan Hassan H, Makary Chadi A

机构信息

School of Medicine West Virginia University Morgantown West Virginia USA.

Department of Otolaryngology-Head and Neck Surgery West Virginia University Morgantown West Virginia USA.

出版信息

Laryngoscope Investig Otolaryngol. 2025 Jul 23;10(4):e70211. doi: 10.1002/lio2.70211. eCollection 2025 Aug.

Abstract

INTRODUCTION

The need for surgical intervention in patients with recurrent acute rhinosinusitis (RARS) is not well defined. The goal of this study is to understand the different factors that predict receiving surgical intervention in patients with RARS.

METHODS

Retrospective cohort study of adult patients presenting with RARS with at least one objective evidence of rhinosinusitis. Patient characteristics and comorbidities were reviewed. The 22-item sinonasal outcome test (SNOT-22) and endoscopy scores were collected at baseline. Surgical intervention consisted of functional endoscopic sinus surgery (FESS) with or without septoplasty.

RESULTS

One hundred and eighteen patients were included, of which 53 patients underwent surgical intervention during a mean follow-up period of 5.4 (±5.3) months. Patients who underwent surgery were significantly younger (30.0 vs. 48.8,  < 0.01), had higher BMI (43.1 vs. 31.9, < 0.01), higher CT LM scores (5.3 vs. 2.7,  < 0.01), and were more likely to have nasal septal deviation (NSD) (64.2% vs. 41.5%,  = 0.01). Gender, endoscopy scores, SNOT-22 total and domain scores, and rates of other medical comorbidities did not significantly differ by cohort ( > 0.05 for all). On multivariate analysis, age (OR = 0.89, 95% CI: 0.85, 0.94), BMI (1.05, 95% CI: 1.05, 1.18), CT scores (OR = 1.28, 95% CI: 1.10, 1.48), and NSD (3.52, 95% CI: 1.10, 11.28) remained significant predictors for surgical intervention in patients with RARS.

CONCLUSION

RARS patients who proceed to surgical intervention are younger, have higher BMI, and have higher objective disease burden, including evidence of NSD and higher CT LM scores.

LEVEL OF EVIDENCE

摘要

引言

复发性急性鼻-鼻窦炎(RARS)患者手术干预的必要性尚未明确界定。本研究的目的是了解预测RARS患者接受手术干预的不同因素。

方法

对患有RARS且有至少一项鼻窦炎客观证据的成年患者进行回顾性队列研究。回顾患者的特征和合并症。在基线时收集22项鼻窦结局测试(SNOT-22)和内镜评分。手术干预包括功能性内镜鼻窦手术(FESS),可伴或不伴鼻中隔成形术。

结果

共纳入118例患者,其中53例患者在平均5.4(±5.3)个月的随访期内接受了手术干预。接受手术的患者明显更年轻(30.0对48.8,P<0.01),BMI更高(43.1对31.9,P<0.01),CT LM评分更高(5.3对2.7,P<0.01),并且更有可能存在鼻中隔偏曲(NSD)(64.2%对41.5%,P = 0.01)。性别、内镜评分、SNOT-22总分和各领域评分以及其他内科合并症的发生率在不同队列之间无显著差异(所有P>0.05)。多因素分析显示,年龄(OR = 0.89,95%CI:0.85,0.94)、BMI(1.05,95%CI:1.05,1.18)、CT评分(OR = 1.28,95%CI:1.10,1.48)和NSD(3.52,95%CI:1.10,11.28)仍然是RARS患者手术干预的显著预测因素。

结论

接受手术干预的RARS患者更年轻,BMI更高,客观疾病负担更重,包括存在NSD和更高的CT LM评分证据。

证据级别

4级

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cfa/12284732/d45e5569cf57/LIO2-10-e70211-g002.jpg

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