Wu Yangzong, Hong Shuting, Zheng Limei, Chen Xiaoxin, Fan Zhiquan, Wu Qiangwang, Luo Congli
Department of Neurosurgery, the Second Hospital of Longyan, China.
Department of Neurosurgery, the First Affiliated Hospital of Fujian Medical University, China.
J Int Med Res. 2025 Jul;53(7):3000605251358034. doi: 10.1177/03000605251358034. Epub 2025 Jul 24.
A middle-aged (46 years old) woman had been experiencing recurrent upper abdominal distension, nausea, and belching over a 2-year period. She underwent extensive gastrointestinal evaluations, including endoscopy, chest computed tomography, and abdominal ultrasound; she was diagnosed with chronic gastritis and treated with omeprazole (20 mg bid) and mosapride (5 mg tid) for 1 month, with no symptom relief. For further diagnosis and treatment, she visited The Second Hospital of Longyan in April 2023. Further investigations, including brain imaging and video electroencephalography, revealed medial temporal lobe cavernous malformation associated with epilepsy. She subsequently underwent expanded medial temporal lobectomy for removal of the lesion and the surrounding epileptogenic cortex. Postoperatively, her gastrointestinal symptoms resolved completely. This case highlights the importance of considering medial temporal lobe epilepsy in the differential diagnosis of patients presenting with recurrent, short-duration gastrointestinal complaints that are not resolved with conventional treatments.
一名中年（46岁）女性在两年时间里反复出现上腹胀、恶心和嗳气症状。她接受了包括内镜检查、胸部计算机断层扫描和腹部超声在内的广泛胃肠道评估；被诊断为慢性胃炎，并用奥美拉唑（20毫克，每日两次）和莫沙必利（5毫克，每日三次）治疗1个月，但症状未缓解。为进一步诊断和治疗，她于2023年4月就诊于龙岩市第二医院。进一步检查，包括脑部成像和视频脑电图检查，发现内侧颞叶海绵状畸形伴癫痫。随后，她接受了扩大内侧颞叶切除术以切除病变及周围致痫皮层。术后，她的胃肠道症状完全消失。该病例强调了在鉴别诊断反复出现、持续时间短且常规治疗无法缓解的胃肠道症状患者时，考虑内侧颞叶癫痫的重要性。
