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[德国的真菌性角膜炎:诊断、保守治疗及显微手术治疗]

[Fungal keratitis in Germany : Diagnostics, conservative and microsurgical treatment].

作者信息

Seitz Berthold, Abu Dail Y, Berger T, Suffo S, Flockerzi E, Flockerzi F, Daas L

机构信息

Klinik für Augenheilkunde und Hochschulambulanz, Universitätsklinikum des Saarlandes UKS, Head of IOFF Fellowships, Kirrberger Str. 100, 66421, Homburg/Saar, Deutschland.

Institut für Allgemeine und Spezielle Pathologie, Universitätsklinikum des Saarlandes UKS, Homburg/Saar, Deutschland.

出版信息

Ophthalmologie. 2025 Jul 24. doi: 10.1007/s00347-025-02274-y.

Abstract

Fungal keratitis is still a relatively rare but very serious ophthalmological condition with a potentially vision-threatening course, possibly including even loss of the eye. Similar to acanthamoeba keratitis, it is often initially misdiagnosed with the slit lamp. For more than 20 years an increase in the incidence of fungal keratitis has been observed, also in Germany possibly due to the increased use of soft contact lenses and climate change. This article provides an overview of the typical clinical signs and symptoms of keratomycosis and presents the latest findings in the field of diagnostics as well as drug and, in particular microsurgical treatment. A special focus is placed on the indications and technique of emergency keratoplasty (à chaud) for fungal keratitis and its postoperative care.

摘要

真菌性角膜炎仍然是一种相对罕见但非常严重的眼科疾病,其病程可能威胁视力,甚至可能导致失明。与棘阿米巴角膜炎类似,它最初常被裂隙灯误诊。20多年来,真菌性角膜炎的发病率一直在上升,在德国可能也是由于软性隐形眼镜使用增加和气候变化所致。本文概述了角膜真菌病的典型临床体征和症状,介绍了诊断领域以及药物治疗,特别是显微外科治疗的最新研究结果。特别关注真菌性角膜炎紧急角膜移植术(即刻)的适应症和技术及其术后护理。

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