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镰刀菌角膜炎发病率上升——临床综述

Fusarium Keratitis on the Rise - a Clinical Review.

机构信息

Augenklinik, UniversitätsKlinikum Heidelberg, Deutschland.

出版信息

Klin Monbl Augenheilkd. 2024 Aug;241(8):955-963. doi: 10.1055/a-2120-7752. Epub 2023 Sep 6.

Abstract

Fungal keratitis due to Fusarium species is a rare but serious ocular disease. Due to its rapid progression, often late diagnostic confirmation as well as limited topical treatment options, this is potentially sight threatening. Increasing contact lens use and global climate change have been suggested to be factors leading to an increase in cases of fusarium keratitis, even in regions with moderate climate. Early recognition and initiation of antimycotic treatment, as well as early surgical treatment by penetrating keratoplasty are decisive for the outcome.

摘要

由于镰孢菌属引起的真菌性角膜炎是一种罕见但严重的眼部疾病。由于其进展迅速,通常在确诊较晚以及局部治疗选择有限,因此可能会威胁到视力。接触镜使用的增加和全球气候变化被认为是导致镰刀菌角膜炎病例增加的因素,即使在气候温和的地区也是如此。早期识别和开始抗真菌治疗,以及通过穿透性角膜移植进行早期手术治疗,对结果具有决定性意义。

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