Wang Haixia, Yao Yuan, Lv Xiaobing, Yu Meng, Geng Shoumeng, Yong Chunming
Department of Emergency Internal Medicine, The Affiliated Hospital of Qingdao University, No. 16, Jiangsu Road, Shinan District, Qingdao, 266000, Shandong, China.
Department of Rheumatology and Immunology, The Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Rheumatol Int. 2025 Jul 24;45(8):176. doi: 10.1007/s00296-025-05915-2.
Gout is a prevalent chronic metabolic disorder that significantly impairs the quality of life of affected individuals. Enhancing medication adherence among gout patients is crucial for optimizing clinical outcomes. The present study aims to investigate the levels of health empowerment and medication adherence among gout patients and to identify the factors influencing these outcomes. This study recruited gout patients who presented to our hospital between April 2024 and January 2025. Medication adherence and health empowerment were assessed using validated scales. Logistic regression analysis was employed to identify independent risk factors associated with poor medication adherence. A total of 364 gout patients were included in the study. The mean health empowerment score among gout patients was 24.06 ± 5.22. Correlation analysis revealed significant associations between medication adherence and several variables, including residence, per capita monthly income, duration of gout, number of gout flares in the past year, and health empowerment level. Residence (OR = 2.812, 95% CI: 2.180 ~ 3.445), per capita monthly income (OR = 1.935, 95% CI: 1.006 ~ 2.482), duration of gout (OR = 1.823, 95% CI: 1.311 ~ 2.246), number of gout flares in the past year (OR = 2.412, 95% CI: 1.856 ~ 3.205), and health empowerment level (OR = 3.547, 95% CI: 2.664 ~ 4.862) were significant influencing factors of medication adherence in gout patients. The findings indicate that both medication adherence and health empowerment levels are suboptimal among gout patients. These results highlight the importance of prioritizing health empowerment education and improving medication adherence in clinical practice.
痛风是一种常见的慢性代谢性疾病，严重影响患者的生活质量。提高痛风患者的药物依从性对于优化临床治疗效果至关重要。本研究旨在调查痛风患者的健康赋权水平和药物依从性，并确定影响这些结果的因素。本研究招募了2024年4月至2025年1月期间到我院就诊的痛风患者。使用经过验证的量表评估药物依从性和健康赋权情况。采用逻辑回归分析确定与药物依从性差相关的独立危险因素。本研究共纳入364例痛风患者。痛风患者的平均健康赋权得分为24.06±5.22。相关性分析显示，药物依从性与多个变量之间存在显著关联，包括居住地、人均月收入、痛风病程、过去一年痛风发作次数和健康赋权水平。居住地（OR = 2.812，95%CI：2.180～3.445）、人均月收入（OR = 1.935，95%CI：1.006～2.482）、痛风病程（OR = 1.823，95%CI：1.311～2.246）、过去一年痛风发作次数（OR = 2.412，95%CI：1.856～3.205）和健康赋权水平（OR = 3.547，95%CI：2.664～4.862）是痛风患者药物依从性的显著影响因素。研究结果表明，痛风患者的药物依从性和健康赋权水平均不理想。这些结果凸显了在临床实践中优先开展健康赋权教育和提高药物依从性的重要性。
