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抑郁和赋权对乳腺癌患者药物依从性的影响:一项描述性调查。

Effect of depression and empowerment on medication adherence in patients with breast cancer: a descriptive survey.

作者信息

Jeong Sookyung, Kim Eun Jeong

机构信息

Department of Nursing, College of Medicine, Wonkwang University, 460, Iksandae-ro, Iksan, Jeonbuk, 54538, Republic of Korea.

Wonkwang University Hospital, Iksan, South Korea.

出版信息

BMC Nurs. 2025 Jan 14;24(1):47. doi: 10.1186/s12912-024-02680-8.

Abstract

BACKGROUND

Given the global prevalence of breast cancer and its high mortality rate, adherence to long-term anti-hormonal therapy is crucial for preventing recurrence and improving survival outcomes. Previous research demonstrates how psychological factors including depression and empowerment impact medication adherence. However, comprehensive studies remain limited, especially in Korea. This study explores the effects of depression and empowerment on medication adherence among patients with breast cancer undergoing anti-hormonal therapy.

METHODS

This descriptive survey involved 183 patients with breast cancer from one hospital in South Korea; participants were recruited using convenience sampling. Self-reported questionnaires were used to assess medication adherence, depression levels using the Korean version of the Beck Depression Inventory-II, and empowerment levels using a tool developed for women with breast cancer. Hierarchical regression explored relationships and influences between variables.

RESULTS

Participants demonstrated an average depression score of 19.67 ± 11.25, with medication adherence measured at 18.06 ± 5.15 and empowerment at 106.40 ± 18.15, revealing that, among patients with breast cancer, many experienced depression with varying levels: 16.9% mild, 27.3% moderate, and 21.9% severe. Medication adherence levels were distributed, with 58.5% of patients categorized as non-adherent and 41.5% categorized as adherent. The results indicated a significant negative correlation between depression and medication adherence and a positive correlation between empowerment and medication adherence. Higher empowerment levels were associated with improved adherence. Conversely, high depression levels were associated with low medication adherence.

CONCLUSIONS

This study enhances understandings of psychosocial factors influencing medication adherence in patients with breast cancer, highlighting patient empowerment as crucial for healthcare interventions. Thus, healthcare providers should implement targeted interventions including educational programs to inform patients about their treatment regimens, provide counseling services addressing mental health concerns such as depression, and establish support groups fostering a sense of community and shared experiences among patients. By integrating these strategies into patient care, healthcare professionals can significantly enhance patient empowerment and improve medication adherence toward better health outcomes for breast cancer patients. Future research could explore the long-term effects of these interventions on adherence and overall patient well-being.

摘要

背景

鉴于乳腺癌在全球的患病率及其高死亡率,坚持长期抗激素治疗对于预防复发和改善生存结局至关重要。先前的研究表明,包括抑郁和赋权在内的心理因素如何影响药物依从性。然而,全面的研究仍然有限,尤其是在韩国。本研究探讨抑郁和赋权对接受抗激素治疗的乳腺癌患者药物依从性的影响。

方法

这项描述性调查涉及韩国一家医院的183名乳腺癌患者;采用便利抽样法招募参与者。使用自我报告问卷评估药物依从性,使用韩国版贝克抑郁量表-II评估抑郁水平,使用为乳腺癌女性开发的工具评估赋权水平。分层回归探讨变量之间的关系和影响。

结果

参与者的平均抑郁评分为19.67±11.25,药物依从性评分为18.06±5.15,赋权评分为106.40±18.15,这表明,在乳腺癌患者中,许多人经历了不同程度的抑郁:16.9%为轻度,27.3%为中度,21.9%为重度。药物依从性水平分布如下,58.5%的患者被归类为不依从,41.5%的患者被归类为依从。结果表明,抑郁与药物依从性之间存在显著负相关,赋权与药物依从性之间存在正相关。更高的赋权水平与更好的依从性相关。相反,高抑郁水平与低药物依从性相关。

结论

本研究增进了对影响乳腺癌患者药物依从性的社会心理因素的理解,强调患者赋权对医疗干预至关重要。因此,医疗服务提供者应实施有针对性的干预措施,包括开展教育项目,让患者了解其治疗方案,提供咨询服务以解决抑郁等心理健康问题,并建立支持小组,增强患者的社区意识和共同体验。通过将这些策略融入患者护理中,医疗专业人员可以显著增强患者赋权,提高药物依从性,从而为乳腺癌患者带来更好的健康结局。未来的研究可以探讨这些干预措施对依从性和患者整体幸福感的长期影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f61/11731554/8872f6d05739/12912_2024_2680_Fig1_HTML.jpg

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