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为印度早产儿视网膜病变致盲问题构建无盲未来:进展、挑战与前行之路

Building a Future without Blindness due to Retinopathy of Prematurity in India: Progress, Challenges, and the Way Forward.

作者信息

Kumar Jogender, Kumar Praveen, Deorari Ashok Kumar

机构信息

Neonatal Unit, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India.

出版信息

Indian Pediatr. 2025 Jul 24. doi: 10.1007/s13312-025-00142-1.

DOI:10.1007/s13312-025-00142-1
PMID:40705223
Abstract

Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness in India. We examined the progress, current status, and challenges related to ROP in India. Despite national guidelines and initiatives, the coverage of ROP screening remains highly variable across regions. Key challenges include lack of screening facilities, trained personnel, inadequate awareness, and delayed referrals. Successful strategies include capacity building, quality improvement approaches, and telescreening. We recommend policy actions, including mandatory ROP screening arrangements by neonatal care facilities, raising community awareness, and the inclusion of ROP indicators in health system monitoring. Leveraging digital technologies and focusing on primary prevention through improved quality of neonatal care are crucial. With sustained commitment and intersectoral collaboration, India can create a comprehensive model for neonatal eye care for low- and middle-income countries, preventing ROP-related visual impairment and ensuring the right to sight for all infants.

摘要

早产儿视网膜病变(ROP)是印度儿童可预防失明的主要原因。我们研究了印度与ROP相关的进展、现状和挑战。尽管有国家指南和倡议,但ROP筛查的覆盖率在各地区仍存在很大差异。主要挑战包括缺乏筛查设施、训练有素的人员、认识不足以及转诊延迟。成功的策略包括能力建设、质量改进方法和远程筛查。我们建议采取政策行动,包括新生儿护理机构进行强制性ROP筛查安排、提高社区认识以及将ROP指标纳入卫生系统监测。利用数字技术并通过提高新生儿护理质量专注于一级预防至关重要。通过持续的承诺和部门间合作,印度可以为低收入和中等收入国家创建一个全面的新生儿眼保健模式,预防与ROP相关的视力损害,并确保所有婴儿的视力权。

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Building a Future without Blindness due to Retinopathy of Prematurity in India: Progress, Challenges, and the Way Forward.为印度早产儿视网膜病变致盲问题构建无盲未来:进展、挑战与前行之路
Indian Pediatr. 2025 Jul 24. doi: 10.1007/s13312-025-00142-1.
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本文引用的文献

1
Outcome of real-time telescreening for retinopathy of prematurity using videoconferencing in a community setting in Eastern India.在印度东部社区环境中使用视频会议进行早产儿视网膜病变实时远程筛查的结果。
Indian J Ophthalmol. 2024 May 1;72(5):697-703. doi: 10.4103/IJO.IJO_2024_23. Epub 2024 Feb 23.
2
Diagnostic Accuracy of Pediatrician-performed Digital Retinal Imaging with 3nethra neo for ROP Screening.儿科医生使用3nethra neo进行数字视网膜成像筛查视网膜病变的诊断准确性。
Indian J Pediatr. 2025 Jun;92(6):605-611. doi: 10.1007/s12098-024-05042-z. Epub 2024 Feb 19.
3
Development and validation of an artificial intelligence based screening tool for detection of retinopathy of prematurity in a South Indian population.
基于人工智能的筛查工具在南印度人群中检测早产儿视网膜病变的开发与验证
Front Pediatr. 2023 Sep 19;11:1197237. doi: 10.3389/fped.2023.1197237. eCollection 2023.
4
Retinopathy of prematurity in India - what can we learn from the polio legacy?印度的早产儿视网膜病变——我们能从脊髓灰质炎的遗留问题中学到什么?
Lancet Reg Health Southeast Asia. 2023 May 10;14:100210. doi: 10.1016/j.lansea.2023.100210. eCollection 2023 Jul.
5
Incidence, Characteristics and Risk Factors of Retinopathy of Prematurity in an Exclusive Cohort of Infants with Birthweight More than 1500 g.出生体重超过1500克的婴儿专属队列中早产儿视网膜病变的发病率、特征及危险因素
Indian J Pediatr. 2023 Jun;90(6):628. doi: 10.1007/s12098-023-04534-8. Epub 2023 Mar 23.
6
Improving the Quality of Health Care in Special Neonatal Care Units of India: A Before and After Intervention Study.改善印度特殊新生儿护理单元的医疗质量:一项干预前后研究。
Glob Health Sci Pract. 2022 Oct 31;10(5). doi: 10.9745/GHSP-D-22-00085.
7
Beyond Fetal Immunity: A Systematic Review and Meta-Analysis of the Association Between Antenatal Corticosteroids and Retinopathy of Prematurity.超越胎儿免疫:关于产前皮质类固醇与早产儿视网膜病变关联的系统评价和荟萃分析
Front Pharmacol. 2022 Jan 28;13:759742. doi: 10.3389/fphar.2022.759742. eCollection 2022.
8
Rationalising oxygen usage in a level II special newborn care unit in Madhya Pradesh, India.在印度中央邦的二级特殊新生儿护理单元中合理使用氧气。
BMJ Open Qual. 2021 Jul;10(Suppl 1). doi: 10.1136/bmjoq-2021-001386.
9
Five-year demographic profile of retinopathy of prematurity at a tertiary care institute in North India.印度北部一家三级保健机构早产儿视网膜病变的 5 年人口统计学特征。
Indian J Ophthalmol. 2021 Aug;69(8):2127-2131. doi: 10.4103/ijo.IJO_132_21.
10
ROP screening and treatment in four district-level special newborn care units in India: a cross-sectional study of screening and treatment rates.ROP 筛查与治疗在印度四个地区级特殊新生儿护理单位中的应用:一项关于筛查与治疗率的横断面研究。
BMJ Paediatr Open. 2021 Mar 10;5(1):e000930. doi: 10.1136/bmjpo-2020-000930. eCollection 2021.