Li Ya, Yang Wei, Feng Weiwei, Zhang Lingyuan, Yao Yikun, Yan Kai, Zhang Hong, Wan Xiaochao
2nd Department of Respiratory and Critical Care Medicine, Baoding No. 1 Central Hospital, Baoding, Hebei, China.
Department of Nephrology, Baoding No. 1 Central Hospital, Baoding, Hebei, China.
Front Med (Lausanne). 2025 Jul 10;12:1629264. doi: 10.3389/fmed.2025.1629264. eCollection 2025.
This observational study sought to explore the prevalence and determinants of demoralization syndrome (DS) among elderly patients in North China diagnosed with advanced lung cancer (ALC), with the primary goal of mitigating their psychological distress.
A convenience sampling approach was employed to recruit 420 ALC patients aged 60 years or older from four tertiary hospitals in North China. Data collection was carried out using structured questionnaires, which included the Chinese adaptation of the Demoralization Syndrome Scale and Perceptions of Social Support Questionnaire. Statistical analyses were performed using SPSS 26.0 software to derive meaningful insights.
Univariate analysis identified several significant factors influencing DS levels, including gender, smoking, average monthly household income, living alone, stage of cancer, social support, and self-management abilities. The mean DS score was notably elevated, with 32.8% of participants scoring within the high DS range. Multivariable linear regression analysis further established gender, average monthly household income, stage of cancer, social support, and self-management abilities as independent predictors of DS severity.
The findings highlight the critical importance of addressing socioeconomic factors such as household income, strengthening social support networks, improving self-management skills, and implementing targeted interventions for female patients to reduce DS levels and alleviate psychological distress in elderly ALC patients, particularly those with stage IV cancer. These insights provide valuable guidance for healthcare professionals aiming to enhance the overall well-being of this high-risk population.
本观察性研究旨在探讨中国北方被诊断为晚期肺癌（ALC）的老年患者中士气低落综合征（DS）的患病率及其决定因素，主要目标是减轻他们的心理困扰。
采用便利抽样法，从中国北方的四家三级医院招募了420名60岁及以上的ALC患者。使用结构化问卷进行数据收集，其中包括士气低落综合征量表的中文版和社会支持感知问卷。使用SPSS 26.0软件进行统计分析以得出有意义的见解。
单因素分析确定了几个影响DS水平的重要因素，包括性别、吸烟、家庭月平均收入、独居、癌症分期、社会支持和自我管理能力。DS平均得分显著升高，32.8%的参与者得分处于高DS范围内。多变量线性回归分析进一步确定性别、家庭月平均收入、癌症分期、社会支持和自我管理能力是DS严重程度的独立预测因素。
研究结果突出了应对家庭收入等社会经济因素、加强社会支持网络、提高自我管理技能以及对女性患者实施针对性干预措施以降低DS水平并减轻老年ALC患者，特别是IV期癌症患者心理困扰的至关重要性。这些见解为旨在提高这一高危人群整体福祉的医疗保健专业人员提供了宝贵的指导。
