Javed Nismat, Pineda Rosanna, Itare Vikram, Ashraf Shoaib, Kamalakkannan Gayathri
Internal Medicine, BronxCare Health System, Icahn School of Medicine at Mount Sinai, New York City, USA.
Internal Medicine, BronxCare Health System, New York City, USA.
Cureus. 2025 Jun 24;17(6):e86671. doi: 10.7759/cureus.86671. eCollection 2025 Jun.
Rheumatic heart disease (RHD) affects many people globally, with the majority of cases in low- and middle-income countries. The disease often leads to significant valve damage, requiring surgical intervention due to complications such as regurgitation or stenosis. Although new cases have declined in high-income countries due to improved control of rheumatic fever (RF), chronic RHD remains a concern. Limited data on RHD in the US highlights the need for improved understanding and management. This case report discusses a 49-year-old male with worsening dyspnea, productive cough, and bilateral leg swelling who was diagnosed with severe mitral stenosis and regurgitation secondary to RHD. Diagnostic imaging revealed significant valve dysfunction and thrombi in the left atrial appendage, as confirmed by both echocardiography and a transesophageal echocardiogram. Despite initial management with medications and anticoagulation, the patient was transferred to a tertiary center for potential mitral valve intervention. This case highlights the importance of early identification and multimodal imaging in managing RHD, as well as the ongoing debate regarding the efficacy of mitral valve repair versus replacement.
风湿性心脏病(RHD)在全球影响着众多人群,其中大多数病例发生在低收入和中等收入国家。该疾病常导致严重的瓣膜损害,因反流或狭窄等并发症而需要进行手术干预。尽管由于风湿热(RF)控制的改善,高收入国家的新发病例有所下降,但慢性RHD仍然令人担忧。美国关于RHD的有限数据凸显了加强认识和管理的必要性。本病例报告讨论了一名49岁男性,他出现呼吸困难加重、咳痰、双侧腿部肿胀,被诊断为继发于RHD的严重二尖瓣狭窄和反流。诊断性成像显示存在明显的瓣膜功能障碍以及左心耳血栓,经超声心动图和经食管超声心动图均得以证实。尽管最初采用药物和抗凝治疗,但该患者仍被转至三级中心,以便进行可能的二尖瓣干预。本病例突出了早期识别和多模态成像在RHD管理中的重要性,以及关于二尖瓣修复与置换疗效的持续争论。