Abiyu Sembeto Yalew, Jibril Yousuf Yasmin, Sibhatu Lobago Demeke
Ethiopian Institute of Agricultural Research, Pawe Agricultural Research Center, Pawe, Ethiopia.
College of Veterinary Medicine and Agriculture, Addis Ababa University, Bishoftu, Ethiopia.
Vet Med Sci. 2025 Sep;11(5):e70489. doi: 10.1002/vms3.70489.
Ethiopia has a significant number of sheep and goats, though the benefit gained is little because of several diseases, including Peste des Petits Ruminants (PPR). PPR is a highly contagious and economically important transboundary disease of small ruminants, associated with high morbidity and mortality rates.
A cross-sectional study was conducted to estimate seroprevalence of PPR and identify associated risk factors in four Kebeles of the Pawe district, Northwest Ethiopia.
A total of 334 serum samples (146 from goats and 188 from sheep) were collected and tested for PPRV antibodies using competitive ELISA (c-ELISA).
Out of a total of 334 blood sera from sheep and goats tested for PPR virus antibodies, 236 (70.7%) were positive. There was no significant difference in prevalence between sheep (71.3%) and goats (69.9%). A significantly higher PPRV seroprevalence was observed in female sheep (75.7%) compared to male sheep (55%). Similarly, female goats had a higher prevalence (74.4%) than male goats (48%) (p value = 0.01). The prevalence was also significantly higher in lactating female sheep (81.8%) and goats (83.3%). Age-wise, seroprevalence was higher in older sheep (82.2%, odds ratios [OR] = 4.4) and older goats (84.1%, OR = 5.4) than their younger counterparts. The prevalence was higher in Almu Kebele (82.5%) (χ = 7.5, p value = 0.05). Flock size, age, body condition, origin and the introduction of new animals were identified as potential risk factors associated with the prevalence.
PPR is highly prevalent in the district, indicating significant circulation of the virus in the area. This high prevalence, combined with the regular movement of animals and shared grazing lands in the area, poses a risk for the further spread of the disease. Therefore, priority should be given to the area in control and eradication efforts, along with restrictions on animal movement and targeted vaccination.
埃塞俄比亚拥有大量绵羊和山羊，但由于包括小反刍兽疫（PPR）在内的多种疾病，所获收益甚微。小反刍兽疫是一种小反刍动物的高度传染性且具有重要经济影响的跨界疾病，发病率和死亡率都很高。
开展一项横断面研究，以估计埃塞俄比亚西北部帕韦区四个 Kebeles 的小反刍兽疫血清流行率，并确定相关风险因素。
共采集 334 份血清样本（146 份来自山羊，188 份来自绵羊），并使用竞争 ELISA（c-ELISA）检测小反刍兽疫病毒抗体。
在总共 334 份检测小反刍兽疫病毒抗体的绵羊和山羊血清中，236 份（70.7%）呈阳性。绵羊（71.3%）和山羊（69.9%）的流行率无显著差异。与雄性绵羊（55%）相比，雌性绵羊（75.7%）的小反刍兽疫病毒血清流行率显著更高。同样，雌性山羊（74.4%）的流行率高于雄性山羊（48%）（p 值 = 0.01）。泌乳期雌性绵羊（81.8%）和山羊（83.3%）的流行率也显著更高。按年龄划分，老年绵羊（82.2%，优势比[OR]=4.4）和老年山羊（84.1%，OR=5.4）的血清流行率高于幼年绵羊和山羊。Almu Kebele 的流行率更高（82.5%）（χ=7.5，p 值 = 0.05）。畜群规模、年龄、身体状况、来源以及新动物的引入被确定为与流行率相关的潜在风险因素。
小反刍兽疫在该地区高度流行，表明该病毒在该地区大量传播。这种高流行率，再加上该地区动物的频繁流动和共享牧场，构成了疾病进一步传播的风险。因此，在控制和根除工作中应优先考虑该地区，同时限制动物流动并进行有针对性的疫苗接种。
