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Trans-Epidermal Elimination Due to Insulin Formulation: Report of a Rare Adverse Effect.

作者信息

Samal Abhipsa, Bhoi Aurobinda, Mohanty Jayashree, Behera Swapnarani, Basa Adyasa, Dash Siddhartha

机构信息

Department of Dermatology, and Venereology, Srirama Chandra Bhanja Medical College and Hospital, Cuttack, Odisha, India.

出版信息

Indian Dermatol Online J. 2025 Sep 1;16(5):844-846. doi: 10.4103/idoj.idoj_731_24. Epub 2025 Jul 16.

DOI:10.4103/idoj.idoj_731_24
PMID:40709848
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12419725/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae5/12419725/f9b97ec88b2f/IDOJ-16-844-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae5/12419725/65f97fad32d7/IDOJ-16-844-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae5/12419725/616c836d0679/IDOJ-16-844-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae5/12419725/f9b97ec88b2f/IDOJ-16-844-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae5/12419725/65f97fad32d7/IDOJ-16-844-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae5/12419725/616c836d0679/IDOJ-16-844-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae5/12419725/f9b97ec88b2f/IDOJ-16-844-g003.jpg

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本文引用的文献

1
Perforating Gout: Expanding the Differential for Transepidermal Elimination.穿通性痛风：扩大经表皮消除的鉴别诊断范围
Dermatopathology (Basel). 2023 Jul 12;10(3):207-218. doi: 10.3390/dermatopathology10030029.
2
Insulin-derived amyloidosis: The insulin ball, amyloidoma.胰岛素源性淀粉样变：胰岛素球、淀粉样瘤。
JAAD Case Rep. 2020 Mar 25;6(4):351-353. doi: 10.1016/j.jdcr.2020.02.011. eCollection 2020 Apr.
3
Exogenous Insulin-Induced Localized Acanthosis Nigricans: A Rare Injection Site Complication.
Can J Diabetes. 2020 Apr;44(3):219-221. doi: 10.1016/j.jcjd.2019.08.010. Epub 2019 Aug 23.
4
Transepidermal elimination: Historical evolution, pathogenesis and nosology.经皮排泄：历史演变、发病机制与疾病分类学
Indian J Dermatol Venereol Leprol. 2018 Nov-Dec;84(6):753-757. doi: 10.4103/ijdvl.IJDVL_396_17.
5
Phenolic excipients of insulin formulations induce cell death, pro-inflammatory signaling and MCP-1 release.胰岛素制剂中的酚类辅料可诱导细胞死亡、促炎信号传导及单核细胞趋化蛋白-1释放。
Toxicol Rep. 2014 Dec 6;2:194-202. doi: 10.1016/j.toxrep.2014.11.019. eCollection 2015.
6
A Case of Skin, and Secondarily Generalized, Reaction to Insulin Injection.一例胰岛素注射引起的皮肤反应及继发全身性反应。
Clin Diabetes. 2014 Jul;32(3):127-9. doi: 10.2337/diaclin.32.3.127.
7
Successful management of allergy to the insulin excipient metacresol in a child with type 1 diabetes: a case report.1型糖尿病患儿对胰岛素辅料间甲酚过敏的成功管理：一例报告
J Med Case Rep. 2012 Aug 31;6:263. doi: 10.1186/1752-1947-6-263.
8
Epidemiology and risk factors for drug allergy.药物过敏的流行病学和危险因素。
Br J Clin Pharmacol. 2011 May;71(5):684-700. doi: 10.1111/j.1365-2125.2010.03774.x.
9
Acquired reactive perforating collagenosis in an insulin dependent diabetes mellitus patient.一名胰岛素依赖型糖尿病患者的获得性反应性穿通性胶原病
J Indian Med Assoc. 2009 Nov;107(11):825-6.
10
Skin-related complications of insulin therapy: epidemiology and emerging management strategies.胰岛素治疗的皮肤相关并发症：流行病学及新出现的管理策略
Am J Clin Dermatol. 2003;4(10):661-7. doi: 10.2165/00128071-200304100-00001.