Dłucik Robert, Firlej Marcel, Bogus Katarzyna, Dłucik Daniel, Orzechowska-Wylęgała Bogusława
Dłucik Dental Clinic, 40-737 Katowice, Poland.
Department of Orthodontics and Craniofacial Anomalies, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
J Funct Biomater. 2025 Jun 25;16(7):233. doi: 10.3390/jfb16070233.
This study aimed to compare the efficacy of Sticky Tooth (ST) derived from ground teeth and Sticky Bone (SB) based on equine bone and human allograft in maxillary bone defect regeneration through histological examination.
Forty patients underwent maxillary alveolar ridge regeneration using four different biomaterials: Sticky Tooth processed with the BonMaker device ( = 10), Sticky Tooth prepared with the Smart Dentin Grinder ( = 10) Sticky Bone derived from an equine xenograft ( = 10), and Sticky Bone derived from human allografts ( = 10). CBCT imaging was performed preoperatively, post-regeneration, and during follow-up. Histological and quantitative statistical evaluation was conducted on biopsy samples obtained four months post-regeneration at the time of implant placement.
Successful alveolar ridge regeneration was achieved in all 40 patients. Histological analyses confirmed good integration between the biomaterials and bone tissue without signs of inflammation.
Histological comparisons demonstrated that both ST and SB are effective biomaterials for bone regeneration. However, ST exhibited a faster bone healing process compared to xenograft and allograft SB.
本研究旨在通过组织学检查,比较源自磨碎牙齿的粘性牙(ST)与基于马骨和人同种异体移植物的粘性骨(SB)在上颌骨缺损再生中的疗效。
40例患者使用四种不同的生物材料进行上颌牙槽嵴再生:用BonMaker设备处理的粘性牙(n = 10)、用智能牙本质研磨机制备的粘性牙(n = 10)、源自马异种移植物的粘性骨(n = 10)以及源自人同种异体移植物的粘性骨(n = 10)。术前、再生后及随访期间进行CBCT成像。在植入种植体时,对再生后四个月获得的活检样本进行组织学和定量统计评估。
40例患者均成功实现牙槽嵴再生。组织学分析证实生物材料与骨组织之间良好整合,无炎症迹象。
组织学比较表明,ST和SB都是有效的骨再生生物材料。然而,与异种移植物和同种异体移植物SB相比,ST表现出更快的骨愈合过程。