Lee Janet Jisoo, Niu Meigan, Shakir Zinah, Hwang Geelsu, Chung Chun-Hsi, Wolff Mark S, Zheng Zhong, Li Chenshuang
School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Department of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
J Funct Biomater. 2025 Jul 3;16(7):244. doi: 10.3390/jfb16070244.
Fixed orthodontic appliances, which are cemented to tooth surfaces, complicate the maintenance of oral hygiene and create a rough surface that is favorable for bacteria attachment. Additionally, the presence of orthodontic appliances may conceive a unique environment that interacts with cariogenic microorganisms, fostering a distinct microbial ecosystem compared to that of the patients without orthodontic appliances, thus increasing the vulnerability of tooth surfaces to demineralization and caries formation. Silver (Ag) has shown strong antimicrobial effects and has been extensively investigated in the medical field. Here, we aim to review the antibacterial properties and potential side effects of silver nanoparticles (AgNPs) when incorporated into orthodontic bonding reagents. This valuation could contribute to the development of novel bonding reagents designed to prevent the formation of white spot lesions and caries during orthodontic treatments.
固定正畸矫治器通过粘结剂固定在牙齿表面,这使得口腔卫生维护变得复杂,并形成了有利于细菌附着的粗糙表面。此外,正畸矫治器的存在可能营造一个与致龋微生物相互作用的独特环境,与未佩戴正畸矫治器的患者相比,会形成一个独特的微生物生态系统,从而增加牙齿表面脱矿和龋齿形成的易感性。银(Ag)已显示出强大的抗菌作用,并在医学领域得到了广泛研究。在此,我们旨在综述银纳米颗粒(AgNPs)掺入正畸粘结剂后的抗菌特性和潜在副作用。这一评估有助于开发新型粘结剂,以预防正畸治疗期间白斑病变和龋齿的形成。