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银纳米颗粒在正畸粘结剂中的应用。

Usage of Silver Nanoparticles in Orthodontic Bonding Reagents.

作者信息

Lee Janet Jisoo, Niu Meigan, Shakir Zinah, Hwang Geelsu, Chung Chun-Hsi, Wolff Mark S, Zheng Zhong, Li Chenshuang

机构信息

School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Department of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

J Funct Biomater. 2025 Jul 3;16(7):244. doi: 10.3390/jfb16070244.

DOI:10.3390/jfb16070244
PMID:40710458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12295521/
Abstract

Fixed orthodontic appliances, which are cemented to tooth surfaces, complicate the maintenance of oral hygiene and create a rough surface that is favorable for bacteria attachment. Additionally, the presence of orthodontic appliances may conceive a unique environment that interacts with cariogenic microorganisms, fostering a distinct microbial ecosystem compared to that of the patients without orthodontic appliances, thus increasing the vulnerability of tooth surfaces to demineralization and caries formation. Silver (Ag) has shown strong antimicrobial effects and has been extensively investigated in the medical field. Here, we aim to review the antibacterial properties and potential side effects of silver nanoparticles (AgNPs) when incorporated into orthodontic bonding reagents. This valuation could contribute to the development of novel bonding reagents designed to prevent the formation of white spot lesions and caries during orthodontic treatments.

摘要

固定正畸矫治器通过粘结剂固定在牙齿表面，这使得口腔卫生维护变得复杂，并形成了有利于细菌附着的粗糙表面。此外，正畸矫治器的存在可能营造一个与致龋微生物相互作用的独特环境，与未佩戴正畸矫治器的患者相比，会形成一个独特的微生物生态系统，从而增加牙齿表面脱矿和龋齿形成的易感性。银（Ag）已显示出强大的抗菌作用，并在医学领域得到了广泛研究。在此，我们旨在综述银纳米颗粒（AgNPs）掺入正畸粘结剂后的抗菌特性和潜在副作用。这一评估有助于开发新型粘结剂，以预防正畸治疗期间白斑病变和龋齿的形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9609/12295521/904286f7ded1/jfb-16-00244-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9609/12295521/904286f7ded1/jfb-16-00244-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9609/12295521/904286f7ded1/jfb-16-00244-g001.jpg

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本文引用的文献

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Investigation of mechanical properties, remineralization, antibacterial effect, and cellular toxicity of composite orthodontic adhesive combined with silver-containing nanostructured bioactive glass.研究含银纳米结构生物活性玻璃复合正畸粘结剂的机械性能、再矿化作用、抗菌效果和细胞毒性。
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Compressive strength and fluoride release profile of a glass ionomer cement reinforced with silver-hydroxyapatite-silica hybrid nanoparticles: An in vitro study.玻璃离子水门汀增强载银羟基磷灰石-硅纳米杂化颗粒的抗压强度和氟释放性能：一项体外研究。
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添加银纳米颗粒对正畸粘合剂力学性能的影响。
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Orthodontic adhesive loaded with different proportions of ZrO silver-doped nanoparticles: An in vitro μTBS, SEM, EDX, FTIR, and antimicrobial analysis.载不同比例 ZrO 银掺杂纳米粒子的正畸粘结剂：体外 μTBS、SEM、EDX、FTIR 和抗菌分析。
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Mechanical and microbiological properties of orthodontic resin modified with nanostructured silver vanadate decorated with silver nanoparticles (βAgVO).用纳米结构银钒酸负载银纳米粒子（βAgVO）修饰的正畸树脂的机械和微生物性能。
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Raman microscopy evaluation of the preventive effect of a modified orthodontic adhesive with silver nanoparticles on the formation of white spot lesions.拉曼显微镜评估含银纳米颗粒的改良正畸粘合剂对白斑病变形成的预防效果。
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Comparison of the Shear Bond Strength of Orthodontic Composites Containing Silver and Amorphous Tricalcium Phosphate Nanoparticles: an Study.含银和无定形磷酸三钙纳米颗粒的正畸复合材料剪切粘结强度的比较：一项研究。
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Effect of incorporating silica-hydroxyapatite-silver hybrid nanoparticles into the resin-modified glass ionomer on the adhesive remnant index score and shear bond strength of orthodontic metal brackets: An in vitro study.将硅烷化羟基磷灰石-银杂化纳米粒子纳入树脂改良型玻璃离子体对正畸金属托槽黏接残留指数评分和剪切黏结强度的影响：一项体外研究。
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