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超声作为男性避孕的一种新方法。

Ultrasound as a new method of male contraception.

作者信息

Fahim M S, Fahim Z, Harman J, Thompson I, Montie J, Hall D G

出版信息

Fertil Steril. 1977 Aug;28(8):823-31.

PMID:407106
Abstract

Twenty male cats were treated once or twice with 1 watt/sq cm of ultrasound for 10 minutes. Each of 24 male dogs received one to three treatments with 1 watt/sq cm for 10 minutes. Another six dogs were treated with 2 watts/sq cm for 15 minutes. Four Cebus apella monkeys were treated with the same dosage as that used for the cats and dogs. A dosage of 1 watt/sq cm for 10 minutes was also applied to four human patients without the use of anesthetics, and no pain or side effects were noted. In all treated animals as well as in human patients the results indicate that ultrasound significantly suppresses spermatogenesis according to the dosage and frequency of treatment, without any effect on Leydig cells or blood testosterone levels.

摘要

二十只雄性猫接受了一次或两次强度为1瓦/平方厘米的超声波治疗,每次治疗10分钟。二十四只雄性狗每只接受了一至三次强度为1瓦/平方厘米、每次10分钟的治疗。另外六只狗接受了强度为2瓦/平方厘米、持续15分钟的治疗。四只僧帽猴接受了与猫和狗相同剂量的治疗。在未使用麻醉剂的情况下,对四名人类患者也施加了强度为1瓦/平方厘米、持续10分钟的剂量,且未观察到疼痛或副作用。在所有接受治疗的动物以及人类患者中,结果表明,根据治疗剂量和频率,超声波能显著抑制精子发生,而对睾丸间质细胞或血液睾酮水平没有任何影响。

相似文献

1
Ultrasound as a new method of male contraception.超声作为男性避孕的一种新方法。
Fertil Steril. 1977 Aug;28(8):823-31.
2
Establishing the minimum effective dose and additive effects of depot progestin in suppression of human spermatogenesis by a testosterone depot.确定长效睾酮制剂中长效孕激素抑制人类精子发生的最小有效剂量及相加作用。
J Clin Endocrinol Metab. 1996 Nov;81(11):4113-21. doi: 10.1210/jcem.81.11.8923869.
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What's better than the pill, vasectomy, celibacy and rhythm?还有什么比避孕药、输精管切除术、禁欲和安全期避孕法更好的呢?
Esquire. 1975 Jan;83(1):100-2.
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Depot gonadotropin-releasing hormone agonist blunts the androgen-induced suppression of spermatogenesis in a clinical trial of male contraception.在一项男性避孕临床试验中,长效促性腺激素释放激素激动剂可减弱雄激素诱导的精子发生抑制作用。
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Testicular suspension as a method of male contraception: technique and results.睾丸固定术作为一种男性避孕方法:技术与结果
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Effects of chronic testosterone administration in normal men: safety and efficacy of high dosage testosterone and parallel dose-dependent suppression of luteinizing hormone, follicle-stimulating hormone, and sperm production.正常男性长期使用睾酮的效果:高剂量睾酮的安全性和有效性以及黄体生成素、卵泡刺激素和精子生成的平行剂量依赖性抑制
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Therapeutic Ultrasound as a Potential Male Dog Contraceptive: Determination of the Most Effective Application Protocol.治疗性超声作为一种潜在的雄性犬类避孕方法:确定最有效的应用方案。
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Ultrasound as a mechanical method for male dog contraception.超声作为一种公犬避孕的机械方法。
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Testicular heat exposure enhances the suppression of spermatogenesis by testosterone in rats: the "two-hit" approach to male contraceptive development.睾丸受热会增强睾酮对大鼠精子发生的抑制作用:男性避孕药物研发的“双打击”方法。
Endocrinology. 2000 Apr;141(4):1414-24. doi: 10.1210/endo.141.4.7416.

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Effect of direct therapeutic ultrasound exposure of ovaries on histopathology, inflammatory response, and oxidative stress in dogs.
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Animals (Basel). 2022 Nov 14;12(22):3144. doi: 10.3390/ani12223144.
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Therapeutic Ultrasound as a Potential Male Dog Contraceptive: Determination of the Most Effective Application Protocol.治疗性超声作为一种潜在的雄性犬类避孕方法:确定最有效的应用方案。
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The efficacy of ultrasound treatment as a reversible male contraceptive in the rhesus monkey.超声治疗作为可逆性猕猴雄性避孕药的效果。
Reprod Biol Endocrinol. 2012 Sep 12;10:81. doi: 10.1186/1477-7827-10-81.
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Therapeutic ultrasound as a potential male contraceptive: power, frequency and temperature required to deplete rat testes of meiotic cells and epididymides of sperm determined using a commercially available system.超声治疗作为一种潜在的男性避孕药具:使用市售系统确定使大鼠睾丸内减数分裂细胞耗竭和附睾内精子减少所需的功率、频率和温度。
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