James Deepa, Joy Anju, Pournami Femitha, Prabhakar Jyothi, Jain Naveen
Department of Neonatology, KIMS Health, Trivandrum, Kerala, 695029, India.
Indian Pediatr. 2025 Jul 25. doi: 10.1007/s13312-025-00131-4.
Preterm survivors are at risk of acquiring communicable diseases post-discharge. Cocoon strategy is immunization of close contacts to prevent infections in such vulnerable individuals. This study assessed the coverage of cocoon vaccines among mothers of very preterm infants.
This retrospective study analyzed the proportion of mothers of very preterm (< 30 weeks) infants who received the eligible cocoon vaccines [tetanus, diphtheria, and acellular pertussis (Tdap), influenza, and varicella] in the antenatal or postnatal period.
Seventy-five out of 159 (47.2%) mothers had received all three cocoon vaccines; the median postnatal age of receiving vaccines was 38 (23, 55) days. Influenza and Tdap vaccines were administered to 64.1% and 48.5% mothers, respectively, either antenatally or postnatally. Only 49.2% (34 out of 69) of the fathers were covered for cocoon vaccines.
Less than 50% mothers were compliant with cocoon vaccination protocol. This calls for more intensive efforts towards improving vaccine coverage among close contacts of high-risk infants.
早产幸存者出院后有感染传染病的风险。“茧式策略”是对密切接触者进行免疫接种，以预防这类易感个体感染。本研究评估了极早产儿母亲中“茧式疫苗”的接种覆盖率。
这项回顾性研究分析了极早产（<30周）婴儿的母亲在产前或产后接受合格“茧式疫苗”[破伤风、白喉和无细胞百日咳（Tdap）、流感和水痘疫苗]的比例。
159名母亲中有75名（47.2%）接种了全部三种“茧式疫苗”；接种疫苗的产后中位年龄为38（23，55）天。分别有64.1%和48.5%的母亲在产前或产后接种了流感疫苗和Tdap疫苗。只有49.2%（69名中的34名）的父亲接种了“茧式疫苗”。
不到50%的母亲遵守“茧式疫苗”接种方案。这就需要做出更大努力，提高高危婴儿密切接触者的疫苗接种覆盖率。
