极早产儿出生后随机接受以捐赠母乳强化剂进行为期2周的早期母乳强化，其支气管肺发育不良的严重程度
Severity of Bronchopulmonary Dysplasia in Infants Born Extremely Preterm and Randomized to Early Human Milk Fortification with a Donor Milk-Derived Fortifier for 2 Weeks.
作者信息
Tucker Marley J, Jeffcoat Seabrook H, Argent Tori, Travers Colm P, Salas Ariel A
机构信息
Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL.
Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL.
出版信息
J Pediatr. 2025 Jul 24;287:114750. doi: 10.1016/j.jpeds.2025.114750.
Abstract
In this secondary analysis of a masked clinical trial involving 150 infants born extremely preterm randomized to receive fortified milk starting on either postnatal day 3 (early group) or day 14 (delayed group), we found a significant difference in the distribution of bronchopulmonary dysplasia severity between the 2 groups (P = .039) with milder forms of bronchopulmonary dysplasia in the early group.
摘要
在这项对一项涉及150名极早产婴儿的双盲临床试验的二次分析中，这些婴儿被随机分为两组，一组从出生后第3天开始接受强化牛奶（早期组），另一组从出生后第14天开始接受强化牛奶（延迟组），我们发现两组之间支气管肺发育不良严重程度的分布存在显著差异（P = 0.039），早期组的支气管肺发育不良形式较轻。
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