Couldrick Jacqui M, Woodward Andrew P, Lynch Joseph T, Brown Nicholas A T, Barton Christian J, Scarvell Jennie M
Faculty of Health, University of Canberra, Canberra, Australia.
Faculty of Health, University of Canberra, Canberra, Australia.
Clin Biomech (Bristol). 2025 Aug;128:106627. doi: 10.1016/j.clinbiomech.2025.106627. Epub 2025 Jul 18.
Evidence links knee joint loads to knee osteoarthritis progression, making load reduction a target for non-surgical interventions. Exercise therapy does not appear to reduce knee joint moments, but studies focus on the medial compartment, overlook severity in other compartments and the influence of body weight, and do not assess more demanding tasks. This study evaluated whether knee adduction and knee flexion moments decrease following exercise therapy. We examined the extent to which knee joint moments change during a more demanding task, chair-rise, and the influence of body weight and osteoarthritis compartment severity.
Thirty-one participants with knee osteoarthritis underwent three-dimensional biomechanical analysis during walking and chair rises at baseline and week-8 after the Good Life with OsteoArthritis in Denmark intervention. Multilevel models estimated knee adduction and knee flexion moments and their relationships with osteoarthritis compartment severity and body weight.
Both knee adduction and knee flexion moments reduced during chair-rise after the intervention. The first peak knee adduction moment increased slightly by 3 % from 41.7 Nm (90 % CrI 37.0, 46.5) to 43.0 Nm (38.5, 47.5) during walking, regardless of osteoarthritis compartment severity. Greater lateral and patellofemoral compartment severity was related to larger knee flexion moment reductions during walking and chair-rises. Weak relationships were found between body weight and knee adduction and knee flexion moments for both tasks. Following the intervention, heavier people had larger increases during walking, but this was uncertain.
Intervention had minimal impact on the knee adduction moment during walking, regardless of compartment severity. Reductions in knee joint moments were observed during chair-rises. Changes in joint load following exercise therapy may be more apparent during demanding tasks. The relationship between knee flexion moment and joint load during demanding tasks warrants further investigation.
有证据表明膝关节负荷与膝关节骨关节炎的进展相关,因此减轻负荷成为非手术干预的目标。运动疗法似乎并不能降低膝关节力矩,但以往研究专注于内侧间室,忽视了其他间室的严重程度以及体重的影响,且未评估更具挑战性的任务。本研究评估了运动疗法后膝关节内收力矩和膝关节屈曲力矩是否会降低。我们研究了在更具挑战性的任务——从椅子上起身过程中膝关节力矩的变化程度,以及体重和骨关节炎间室严重程度的影响。
31名膝关节骨关节炎患者在丹麦骨关节炎美好生活干预的基线期和第8周时,于行走和从椅子上起身过程中接受了三维生物力学分析。多水平模型估计了膝关节内收力矩和膝关节屈曲力矩及其与骨关节炎间室严重程度和体重的关系。
干预后从椅子上起身时,膝关节内收力矩和膝关节屈曲力矩均降低。无论骨关节炎间室严重程度如何,行走过程中膝关节内收力矩的第一个峰值从41.7牛米(90%可信区间37.0,46.5)略微增加了3%,至43.0牛米(38.5,47.5)。外侧间室和髌股间室更严重与行走和从椅子上起身过程中膝关节屈曲力矩的更大降低相关。两项任务中体重与膝关节内收力矩和膝关节屈曲力矩之间的关系较弱。干预后,体重较重者在行走过程中的增加幅度更大,但这一点并不确定。
无论间室严重程度如何,干预对行走过程中的膝关节内收力矩影响极小。从椅子上起身时观察到膝关节力矩降低。运动疗法后关节负荷的变化在具有挑战性的任务中可能更为明显。在具有挑战性的任务中膝关节屈曲力矩与关节负荷之间的关系值得进一步研究。