Howe Jo, Lindsey Laura
Pharmacy School, Aston University, Birmingham, UK.
School of Pharmacy, Newcastle University, Newcastle Upon Tyne, UK.
Soc Psychiatry Psychiatr Epidemiol. 2025 Jul 25. doi: 10.1007/s00127-025-02963-8.
Individuals with serious mental illness (SMI) experience a significantly reduced life expectancy compared to peoplewithout SMI, affecting millions worldwide. While cardiovascular disease, diabetes, and metabolic syndrome are well-recognisedphysical health conditions in this population, this article addresses the unique challenges in managing dementia, cancer,menopause, osteoporosis, and oral health in the context of SMI and ageing.
This article presents a conceptually informed narrative review of ageing-related physical health disparities experiencedby people living with SMI. A narrative review approach was adopted to allow for a targeted and iterative synthesis of evidenceacross five underexplored domains: dementia, cancer, menopause, osteoporosis, and oral health. These domains were selecteddue to their public health significance, under-representation in the literature, and relevance to the lived experiences of older adultswith SMI.
Despite their substantial impact on the well-being of individuals with SMI, these areas often receive less attention.Diagnostic overshadowing, limited specialised knowledge among mental health staff about physical health, and the siloed nature ofhealthcare delivery contribute to delays in diagnosis and treatment.
To improve health outcomes and life expectancy for people with SMI, there is an urgent need for integratedhealthcare approaches. Collaborative models that bridge the gap between mental and physical healthcare are essential to ensuretimely access to holistic care and address the unique needs of this vulnerable population as they age.
与没有严重精神疾病（SMI）的人相比，患有严重精神疾病的人的预期寿命显著缩短，这一情况影响着全球数百万人。虽然心血管疾病、糖尿病和代谢综合征是该人群中公认的身体健康状况，但本文探讨了在严重精神疾病和老龄化背景下管理痴呆症、癌症、更年期、骨质疏松症和口腔健康方面的独特挑战。
本文对患有严重精神疾病的人所经历的与衰老相关的身体健康差异进行了基于概念的叙述性综述。采用叙述性综述方法，以便有针对性地反复综合五个未充分探索领域的证据：痴呆症、癌症、更年期、骨质疏松症和口腔健康。选择这些领域是因为它们具有公共卫生意义、在文献中的代表性不足以及与患有严重精神疾病的老年人的生活经历相关。
尽管这些领域对患有严重精神疾病的人的幸福感有重大影响，但它们往往较少受到关注。诊断遮蔽、心理健康工作人员对身体健康的专业知识有限以及医疗服务的孤立性质导致诊断和治疗延迟。
为了改善患有严重精神疾病的人的健康结果和预期寿命，迫切需要综合医疗保健方法。弥合精神和身体医疗保健之间差距的协作模式对于确保及时获得全面护理以及满足这一弱势群体随着年龄增长的独特需求至关重要。
