Montagnon B J
Trop Geogr Med. 1985 Sep;37(3):S40-1.
In 1980, we presented our preliminary results of large-scale production of Inactivated Polio-Vaccine (IPV). The virus was produced by Vero cells culture grown on micro-carrier in 150 litre tanks; now we produce the poliovirus in 1000 litre tanks. All the tests certifying the 'Cell Bank' have been passed; the quality of purification procedure was demonstrated; additional clinical studies were done; this new reassessed IPV was licensed in France in July 1982.
1980年，我们公布了大规模生产灭活脊髓灰质炎疫苗（IPV）的初步结果。该病毒是通过在150升罐体中的微载体上培养的Vero细胞生产的；现在我们在1000升罐体中生产脊髓灰质炎病毒。所有认证“细胞库”的测试均已通过；纯化程序的质量得到了证明；还进行了额外的临床研究；这种重新评估的新型IPV于1982年7月在法国获得许可。
