Mindlis Irina, Rodebaugh Thomas L, Kiosses Dimitris, Reid M Carrington
Division of Geriatrics and Palliative Medicine, Weill Cornell Medicine, New York, NY, USA.
Department of Psychology and Neuroscience, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
J Appl Gerontol. 2025 Jul 27:7334648251362020. doi: 10.1177/07334648251362020.
For depressed older adults with multimorbidity (OAMM), depression heterogeneity is exacerbated by MM heterogeneity. Individual-level (i.e., ) methods are an unexplored approach to developing tailored treatments for depressed OAMM-we examined their feasibility and acceptability in this population. Ecological momentary assessment (EMA) data were collected from depressed OAMM. Data on depression and MM symptoms were collected for 14 days in three daily surveys. Participants ( = 23, average age 80.5) reported burdensome symptoms of depression and MM at baseline; 19 progressed to the EMA phase, with minimal attrition (5%). EMA adherence was high (89%), as was satisfaction with the study length, burden, and ease of use of the EMA platform. 55% perceived benefit from completing EMA surveys. This study provides preliminary evidence for the feasibility and acceptability of using EMA to assess depressive and MM-related symptoms among OAMM, and lay the groundwork for testing idiographic approaches in this expanding population.
对于患有多种疾病的老年抑郁症患者（OAMM），抑郁症的异质性因多种疾病的异质性而加剧。个体水平（即）方法是为患有抑郁症的OAMM开发量身定制治疗方法的一种未被探索的途径——我们在该人群中研究了它们的可行性和可接受性。从患有抑郁症的OAMM收集了生态瞬时评估（EMA）数据。在每日三次的调查中，持续14天收集了关于抑郁症和多种疾病症状的数据。参与者（n = 23，平均年龄80.5岁）在基线时报告了抑郁症和多种疾病的沉重症状；19人进入了EMA阶段，损耗极小（5%）。EMA依从性很高（89%），对研究时长、负担以及EMA平台易用性的满意度也很高。55%的人认为完成EMA调查有益。本研究为使用EMA评估OAMM中抑郁和与多种疾病相关症状的可行性和可接受性提供了初步证据，并为在这一不断扩大的人群中测试个性化方法奠定了基础。
