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一名患有胎粪性腹膜炎且孕早期感染甲型肝炎的新生儿:病例报告。

A neonate with meconium peritonitis, first-trimester hepatitis A affected pregnancy: A case report.

作者信息

Figueroa Maisonet Lydia L, Mayorga Isabel, Reyes Bou Zayhara, Rivera González Juan Anibal, Ortiz Justiniano Víctor N, Garcia Garcia Inés

机构信息

Medical Sciences Campus, School of Medicine, Pediatrics Department, Neonatology Section, University of Puerto Rico, San Juan, Puerto Rico.

Medical Sciences Campus, School of Medicine, Surgery Department, University of Puerto Rico, San Juan, Puerto Rico.

出版信息

SAGE Open Med Case Rep. 2025 Jul 23;13:2050313X251359725. doi: 10.1177/2050313X251359725. eCollection 2025.

DOI:10.1177/2050313X251359725
PMID:40717837
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12290345/
Abstract

Congenital intra-abdominal masses can stem from various etiologies. However, the differential diagnoses in the presence of meconium peritonitis are primarily narrow to gastrointestinal disorders such as cystic fibrosis, Hirschsprung's disease, and colonic atresia. Additionally, literature has documented rare associations, including maternal hepatitis A infection. We present a case of a premature female infant born via cesarean section to a 25-year-old mother with adequate prenatal care. The mother had a history of flu-like symptoms and diarrhea during the first trimester and routine third-trimester pelvic sonogram findings raised concerns for fetal bowel obstruction or a pelvic mass accompanied by polyhydramnios. The infant presented with a rare occurrence of meconium peritonitis associated with maternal hepatitis A infection. This case is presented to engage and intrigue the medical community. In addition, it suggests that intrauterine exposure to the hepatitis A virus may contribute to fetal intra-abdominal vascular accidents, causing meconium peritonitis.

摘要

先天性腹腔内肿块可源于多种病因。然而,存在胎粪性腹膜炎时的鉴别诊断主要局限于胃肠道疾病,如囊性纤维化、先天性巨结肠和结肠闭锁。此外,文献记载了一些罕见的关联,包括母亲感染甲型肝炎。我们报告一例经剖宫产出生的早产女婴病例,其母亲为25岁,孕期接受了充分的产前护理。母亲在孕早期有类似流感的症状和腹泻病史,孕晚期常规盆腔超声检查结果引发了对胎儿肠梗阻或伴有羊水过多的盆腔肿块的担忧。该婴儿出现了罕见的与母亲甲型肝炎感染相关的胎粪性腹膜炎。本文展示此病例以引起医学界的关注和兴趣。此外,这表明子宫内暴露于甲型肝炎病毒可能导致胎儿腹腔内血管意外,进而引起胎粪性腹膜炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9829/12290345/76f6d5fe818c/10.1177_2050313X251359725-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9829/12290345/7da305bad1b7/10.1177_2050313X251359725-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9829/12290345/76f6d5fe818c/10.1177_2050313X251359725-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9829/12290345/7da305bad1b7/10.1177_2050313X251359725-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9829/12290345/76f6d5fe818c/10.1177_2050313X251359725-fig2.jpg

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