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紫色尿袋综合征:是否进行抗生素治疗?

Purple Urine Bag Syndrome: Antibiotic Treatment or Not?

作者信息

Helmsdal Gunnhild

机构信息

Department of Health Research, National Hospital of the Faroe Islands, Tórshavn, FRO.

出版信息

Cureus. 2025 Jun 25;17(6):e86725. doi: 10.7759/cureus.86725. eCollection 2025 Jun.

DOI:10.7759/cureus.86725
PMID:40718263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12292030/
Abstract

Purple urine bag syndrome (PUBS) is a relatively rare phenomenon characterized by purple discoloration of the urine, catheter, and collection bag in individuals with indwelling catheters often colonized by specific bacteria. Although typically asymptomatic, it requires appropriate diagnostic evaluation and, in some cases, targeted treatment. We present a case study of an 81-year-old male with an indwelling urinary catheter who developed an uncomplicated, self-limiting case of purple urine bag syndrome. The patient exhibited the characteristic purple discoloration of the catheter tubing and collection bag, without accompanying systemic symptoms such as fever, dysuria, flank pain, or altered mental status. This case underscores the importance of recognizing PUBS as a benign condition in many instances, to avoid unnecessary diagnostic testing or antibiotic therapy, while still ensuring appropriate clinical evaluation to rule out potential underlying infections or contributing risk factors.

摘要

紫色尿袋综合征(PUBS)是一种相对罕见的现象,其特征为留置导尿管且常被特定细菌定植的个体出现尿液、导尿管及集尿袋的紫色变色。尽管通常无症状,但它需要进行适当的诊断评估,在某些情况下还需要进行针对性治疗。我们报告一例81岁男性留置导尿管患者发生的无并发症、自限性紫色尿袋综合征病例。该患者导尿管管道和集尿袋呈现特征性的紫色变色,无发热、尿痛、胁腹痛或精神状态改变等伴随全身症状。该病例强调了在许多情况下将PUBS识别为一种良性病症的重要性,以避免不必要的诊断检查或抗生素治疗,同时仍要确保进行适当的临床评估以排除潜在的潜在感染或相关危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5048/12292030/99c26b1e63d3/cureus-0017-00000086725-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5048/12292030/dd7be55e495a/cureus-0017-00000086725-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5048/12292030/99c26b1e63d3/cureus-0017-00000086725-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5048/12292030/dd7be55e495a/cureus-0017-00000086725-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5048/12292030/99c26b1e63d3/cureus-0017-00000086725-i02.jpg

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本文引用的文献

1
Diagnostic Approach to Abnormal Urine Colors: Lessons From a Case of Blue-Green Urine.异常尿液颜色的诊断方法:一例蓝绿色尿液病例的经验教训
Cureus. 2025 Apr 11;17(4):e82122. doi: 10.7759/cureus.82122. eCollection 2025 Apr.
2
A Systematic Literature Review of the Epidemiology of Complicated Urinary Tract Infection.复杂性尿路感染流行病学的系统文献综述
Infect Dis Ther. 2025 Apr 24. doi: 10.1007/s40121-025-01149-8.
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Purple urine bag syndrome: a unique clinical case and management considerations.紫色尿袋综合征:一个独特的临床病例及处理要点。
BMC Nephrol. 2024 Oct 24;25(1):375. doi: 10.1186/s12882-024-03708-6.
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Purple Urine Bag Syndrome Amelioration without Antibiotic Therapy.
J Coll Physicians Surg Pak. 2024 Feb;34(2):248. doi: 10.29271/jcpsp.2024.02.248.
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Acute Hepatic Porphyrias: "Purple Flags"-Clinical Features That Should Prompt Specific Diagnostic Testing.急性肝性血卟啉症:“紫色警报”——提示特定诊断检测的临床特征。
Am J Med Sci. 2022 Jan;363(1):1-10. doi: 10.1016/j.amjms.2021.09.009. Epub 2021 Oct 2.
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A unique case of purple urine: A case report and literature review.紫色尿一例:病例报告及文献复习。
Clin Nephrol. 2021 May;95(5):273-277. doi: 10.5414/CN110272.
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Purple Urine Bag Syndrome: More Than Eyes Can See.紫色尿袋综合征:所见不止于表面
Curr Urol. 2019 Nov;13(3):125-132. doi: 10.1159/000499281. Epub 2019 Nov 13.
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Risk Factors for Nosocomial Bacteremia Secondary to Urinary Catheter-Associated Bacteriuria: A Systematic Review.导尿管相关菌尿继发医院获得性菌血症的危险因素:一项系统评价
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Effectiveness of an Antimicrobial Stewardship Approach for Urinary Catheter-Associated Asymptomatic Bacteriuria.抗菌药物管理策略对无症状性尿导管相关菌尿症的疗效。
JAMA Intern Med. 2015 Jul;175(7):1120-7. doi: 10.1001/jamainternmed.2015.1878.
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Purple urine bag syndrome may not be benign: a case report and brief review of the literature.紫色尿袋综合征可能并非良性:一例病例报告及文献简要综述
Case Rep Infect Dis. 2013;2013:863853. doi: 10.1155/2013/863853. Epub 2013 Jun 20.