Neiroukh Hind, Shatrit Hanin, Sultan Sarmad, Warasna Sarah, Aljodi Maher, Aljodi Tharwat
Alquds University, Abu Dis P144, Palestine.
Cardiovascular surgery Dep, Al-Mezan Hospital, Hebron P7060796, Palestine.
Oxf Med Case Reports. 2025 Jul 27;2025(7):omaf109. doi: 10.1093/omcr/omaf109. eCollection 2025 Jul.
Mycotic aneurysms (MAs) are a rare but life-threatening complication of infective endocarditis (IE), resulting from septic emboli lodging in cerebral vessels and leading to aneurysm formation. This case report describes a 17-year-old female who developed multiple MAs during treatment for IE, resulting in catastrophic neurological decline and eventual death. After undergoing open-heart surgery for vegetation excision, our patient then developed intracranial bleeding due to mycotic aneurysms rupture, which led to her death after an unsuccessful decompressive craniotomy. This case highlights the importance of early recognition and timely intervention in the management of MAs in the context of IE, as well as the need for protocols to improve outcomes in these high-risk patients. The high mortality rate associated with ruptured MAs highlights the critical nature of these complications and the challenges in their management.
真菌性动脉瘤（MAs）是感染性心内膜炎（IE）一种罕见但危及生命的并发症，由脓毒性栓子栓塞脑血管并导致动脉瘤形成所致。本病例报告描述了一名17岁女性，在IE治疗期间发生多发性MAs，导致灾难性神经功能衰退并最终死亡。在接受心脏直视手术切除赘生物后，我们的患者随后因真菌性动脉瘤破裂发生颅内出血，在减压开颅手术失败后死亡。本病例强调了在IE背景下早期识别和及时干预MAs管理的重要性，以及制定改善这些高危患者预后方案的必要性。与破裂的MAs相关的高死亡率凸显了这些并发症的严重性及其管理挑战。
