Pipano E, Krigel Y, Markovics A, Rubinstein E, Frank M
Vet Rec. 1985 Oct 19;117(16):413-4. doi: 10.1136/vr.117.16.413.
Forty 11- to 13-month-old Friesian calves were inoculated with live Babesia bovis vaccine. Twenty of the calves were treated with long acting oxytetracycline seven and 15 days after receiving the vaccine. Parasites were detected in nine of the treated calves compared with all 20 of the untreated control group. Treated calves were less febrile and had higher packed cell volumes than control animals. All calves from both groups developed a considerable antibody titre to B bovis. It appears that long acting oxytetracycline can mitigate the response of sensitive cattle breeds to live antibabesial vaccine and prevent damage caused by excessive multiplication of B bovis parasites.
40头11至13月龄的弗里斯兰犊牛接种了活的牛巴贝斯虫疫苗。其中20头犊牛在接种疫苗后第7天和第15天接受长效土霉素治疗。与未治疗的20头对照组犊牛全部检测到寄生虫相比，治疗组的20头犊牛中有9头检测到了寄生虫。治疗组犊牛发热程度较低，红细胞压积高于对照组动物。两组所有犊牛均产生了较高的抗牛巴贝斯虫抗体效价。长效土霉素似乎可以减轻敏感牛品种对活抗巴贝斯虫疫苗的反应，并防止牛巴贝斯虫寄生虫过度繁殖造成的损害。
