Mohammed Gebaba Ebrahim, Aweke Girma Taye, Addissie Adamu, Assefa Mathewos, Jemal Ahmedin
Department of Reproductive, Family and Population Health, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.
Department of Epidemiology and Biostatistics, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.
PLOS Glob Public Health. 2025 Jul 28;5(7):e0004961. doi: 10.1371/journal.pgph.0004961. eCollection 2025.
Cervical cancer (CCa) is the second leading cause of cancer-related death among women in Addis Ababa and other regions of Ethiopia. The aim of this study was to assess the level of awareness, knowledge, and knowledge of predictors of CCa and screening among women aged 30-49 years in Addis Ababa, Ethiopia. A total of 1980 women aged 30-49 were randomly selected through multistage sampling in Addis Ababa. Data were collected using the Kobo Toolbox after developing and validating the data collection tools. Data were analyzed using SPSS version 26. Logistic regression was used to identify predictors of cervical cancer awareness and knowledge, with a significance level set at a P-value of <0.05. Out of 1,890, 1,881 (99.5%) responded, 1,736 (92.3%) had heard of CCa, 1,015 (54.0%) were aware that Human Papillomavirus (HPV) infection is a risk factor, and 1,237 (65.8%) knew that HPV vaccination prevents CCa. More than half, 1,025 (54.5%) (95%CI = 52.2%-56.8%) had good knowledge of risk factors, 980 (52.1%) (95% CI = 49.8, 54.4%) had poor knowledge of symptoms, and 963 (51.2%) (95% CI = 48.9%, 53.5%) exhibited poor awareness. Overall, 990 (52.6%) (95% CI = 50.4, 54.9%) participants had good knowledge of cervical cancer. Factors such as higher educational attainment (AOR = 2.23; 95% CI: 1.49, 3.34), higher family income (AOR = 1.50; 95%CI: 1.01, 2.23), knowing health facility offering screening (AOR = 1.34; 95% CI: 1.07, 1.68), and knowing someone having cervical cancer (AOR = 5.46; 95% CI: 3.31, 8.97) were significantly associated with overall knowledge levels. Awareness and knowledge about cervical cancer and screening are suboptimal. These findings underscore the need for educational intervention to enhance awareness and knowledge of cervical cancer to reduce the high burden of the disease in the city and other regions of Ethiopia.
宫颈癌（CCa）是亚的斯亚贝巴及埃塞俄比亚其他地区女性癌症相关死亡的第二大主要原因。本研究的目的是评估埃塞俄比亚亚的斯亚贝巴30 - 49岁女性对宫颈癌及其预测因素和筛查的知晓程度、知识水平。通过亚的斯亚贝巴的多阶段抽样共随机选取了1980名30 - 49岁的女性。在开发并验证数据收集工具后，使用Kobo Toolbox收集数据。使用SPSS 26版进行数据分析。采用逻辑回归确定宫颈癌知晓和知识的预测因素，显著性水平设定为P值<0.05。在1890名参与者中，1881名（99.5%）做出了回应，1736名（92.3%）听说过宫颈癌，1015名（54.0%）知道人乳头瘤病毒（HPV）感染是一个风险因素，1237名（65.8%）知道HPV疫苗接种可预防宫颈癌。超过一半，即1025名（54.5%）（95%可信区间 = 52.2% - 56.8%）对风险因素有良好的认知，980名（52.1%）（95%可信区间 = 49.8, 54.4%）对症状的认知较差，963名（51.2%）（95%可信区间 = 48.9%, 53.5%）的知晓程度较差。总体而言，990名（52.6%）（95%可信区间 = 50.4, 54.9%）参与者对宫颈癌有良好的认知。诸如较高的教育程度（比值比 = 2.23；95%可信区间：1.49, 3.34）、较高的家庭收入（比值比 = 1.50；95%可信区间：1.01, 2.23）、知道提供筛查的医疗机构（比值比 = 1.34；95%可信区间：1.07, 1.68）以及认识患宫颈癌的人（比值比 = 5.46；95%可信区间：3.31, 8.97）等因素与总体知识水平显著相关。对宫颈癌及其筛查的知晓和知识情况并不理想。这些发现强调了进行教育干预以提高对宫颈癌的知晓和知识水平的必要性，以减轻该疾病在该市及埃塞俄比亚其他地区的沉重负担。
