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On the mechanism of NPM1 mutations in acute myeloid leukemia.

作者信息

Lieber Michael R, Hsieh Chih-Lin

机构信息

USC Norris Comprehensive Cancer Center and Departments of Pathology, Molecular Microbiology & Immunology, Cancer Biology, and Section of Molecular & Computational Biology (Department of Biological Sciences), Los Angeles, CA, USA.

USC Norris Comprehensive Cancer Center and Department of Urology, University of Southern California, Los Angeles, CA, USA.

出版信息

Leukemia. 2025 Jul 28. doi: 10.1038/s41375-025-02722-3.

DOI:10.1038/s41375-025-02722-3
PMID:40721647
Abstract
摘要

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本文引用的文献

1
Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain.非催化结构域调控 APOBEC3G DNA 编辑功能的分子机制
Nat Commun. 2024 Oct 10;15(1):8773. doi: 10.1038/s41467-024-52671-1.
2
The RNA tether model for human chromosomal translocation fragile zones.人类染色体易位脆性区的 RNA 系绳模型。
Trends Biochem Sci. 2024 May;49(5):391-400. doi: 10.1016/j.tibs.2024.02.003. Epub 2024 Mar 14.
3
The Identification of APOBEC3G as a Potential Prognostic Biomarker in Acute Myeloid Leukemia and a Possible Drug Target for Crotonoside.
APOBEC3G 作为急性髓系白血病潜在预后生物标志物的鉴定及巴豆苷的可能药物靶点
Molecules. 2022 Sep 7;27(18):5804. doi: 10.3390/molecules27185804.
4
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.国际髓系肿瘤和急性白血病分类：整合形态学、临床和基因组数据。
Blood. 2022 Sep 15;140(11):1200-1228. doi: 10.1182/blood.2022015850.
5
The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms.《世界卫生组织造血与淋巴组织肿瘤分类》第五版：淋巴肿瘤。
Leukemia. 2022 Jul;36(7):1720-1748. doi: 10.1038/s41375-022-01620-2. Epub 2022 Jun 22.
6
The mRNA tether model for activation-induced deaminase and its relevance for Ig somatic hypermutation and class switch recombination.激活诱导脱氨酶的mRNA系留模型及其与Ig体细胞高频突变和类别转换重组的相关性。
DNA Repair (Amst). 2022 Feb;110:103271. doi: 10.1016/j.dnarep.2021.103271. Epub 2021 Dec 30.
7
The mechanisms of human lymphoid chromosomal translocations and their medical relevance.人类淋巴染色体易位的机制及其医学相关性。
Crit Rev Biochem Mol Biol. 2022 Jun;57(3):227-243. doi: 10.1080/10409238.2021.2004576. Epub 2021 Dec 7.
8
Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure.APOBEC3 家族成员中的脱氨酶热点由靶序列上下文和单链 DNA 二级结构共同定义。
Nucleic Acids Res. 2020 Feb 20;48(3):1353-1371. doi: 10.1093/nar/gkz1164.
9
The curious incident of TdT-mediated mutations in AML.急性髓系白血病中末端脱氧核苷酸转移酶介导的突变这一奇特事件。
Blood. 2019 Dec 19;134(25):2229-2231. doi: 10.1182/blood.2019003619.
10
Terminal deoxynucleotidyl transferase promotes acute myeloid leukemia by priming FLT3-ITD replication slippage.端粒酶通过引发 FLT3-ITD 复制滑动促进急性髓细胞白血病。
Blood. 2019 Dec 19;134(25):2281-2290. doi: 10.1182/blood.2019001238.