Shariatmadari Hanie, Taheri-Kharameh Zahra, Kamaliuon Noora, Ghanbari Hashem Abadi Bahram Ali, Shokouhi-Tabar Mahmoud
Student Research Committee, Qom University of Medical Sciences, Qom, Iran.
Department of psychology, faculty of psychology and educational science, Allameh Tabataba'i University, Tehran, Iran.
BMC Cancer. 2025 Jul 28;25(1):1226. doi: 10.1186/s12885-025-14492-3.
Breast cancer diagnosis and treatment can lead to significant psychological distress, including anxiety and depression. Positive psychology interventions, such as Gratitude Intervention (GI) and Behavioral Activation (BA), have shown promise in managing mental health issues. This study aims to evaluate and compare the effects of GI and BA on anxiety and depression levels among women with breast cancer.
This study randomly assigned 45 breast cancer patients from a hospital in Mashhad, Iran, into two groups: the gratitude group ( = 22) and the BA group ( = 23). The participants underwent six weekly 45-minute sessions of their respective interventions. The Hospital Anxiety and Depression Scale (HADS) was employed to assess anxiety and depression levels prior to and following the intervention. Statistical analyses were conducted to ascertain the relative effectiveness of the two. methods.
Following the intervention, both the GI and BA groups exhibited a statistically significant reduction in anxiety scores. However, neither intervention led to a statistically significant reduction in depression scores. The mean anxiety scores in the GI group decreased from 19.54 ± 3.63 to 17.00 ± 1.79, while in the BA group, anxiety scores decreased from 21.43 ± 3.65 to 18.73 ± 2.94. The BA group demonstrated a greater reduction in anxiety scores compared to the GI group, with a mean change of 2.70 ± 0.71 versus 2.54 ± 1.84, respectively. This difference was statistically significant ( =.022).
The study suggests that both gratitude exercises and BA may be beneficial in mitigating anxiety among breast cancer patients, with BA demonstrating potentially greater efficacy. However, no significant changes were observed in depression scores. Future studies should include patients with higher levels of depression and longer interventions to more accurately measure the effects of these interventions on depression.
This trial has been retrospectively registered with the Iranian Registry of Clinical Trials (IRCT) under the registration number IRCT20241020063430N1. The registration date is November 21, 2024. The registration can be verified on the IRCT website at [https//irct.behdasht.gov.ir].
乳腺癌的诊断和治疗可能导致严重的心理困扰,包括焦虑和抑郁。积极心理学干预措施,如感恩干预(GI)和行为激活(BA),在管理心理健康问题方面显示出前景。本研究旨在评估和比较GI和BA对乳腺癌女性焦虑和抑郁水平的影响。
本研究将伊朗马什哈德一家医院的45名乳腺癌患者随机分为两组:感恩组(n = 22)和BA组(n = 23)。参与者各自接受为期六周、每周一次、每次45分钟的干预课程。采用医院焦虑抑郁量表(HADS)在干预前后评估焦虑和抑郁水平。进行统计分析以确定两种方法的相对有效性。
干预后,GI组和BA组的焦虑评分均有统计学意义的降低。然而,两种干预均未导致抑郁评分有统计学意义的降低。GI组的平均焦虑评分从19.54±3.63降至17.00±1.79,而BA组的焦虑评分从21.43±3.65降至18.73±2.94。与GI组相比,BA组的焦虑评分降低幅度更大,平均变化分别为2.70±0.71和2.54±1.84。这种差异具有统计学意义(p = 0.022)。
该研究表明,感恩练习和BA可能都有助于减轻乳腺癌患者的焦虑,其中BA显示出可能更大的疗效。然而,抑郁评分未观察到显著变化。未来的研究应纳入抑郁程度更高的患者和更长时间的干预,以更准确地衡量这些干预对抑郁的影响。
本试验已在伊朗临床试验注册中心(IRCT)进行回顾性注册,注册号为IRCT20241020063430N1。注册日期为2024年11月21日。可在IRCT网站[https//irct.behdasht.gov.ir]上核实注册情况。