Ortega-Silva Marcelo, Del Sol Mariano
Programa de Doctorado en Ciencias Morfológicas, Facultad de Medicina, Universidad de La Frontera, Temuco 4780000, Chile.
Departamento de Ciencias Basicas, Facultad de Medicina, Universidad de La Frontera, Temuco 4780000, Chile.
Diagnostics (Basel). 2025 Jul 18;15(14):1814. doi: 10.3390/diagnostics15141814.
Developmental dysplasia of the hip (DDH) affects 1-3% of newborns and requires early detection for optimal outcomes. DDH involves abnormal acetabular-femoral congruence between the acetabulum and femoral head, resulting from either shallow acetabular development or delayed femoral ossification of the femoral head. We evaluated the ossification nucleus of the femoral head (ONFH) to determine prevalence, radiographic timing, and associations with perinatal factors. We analyzed 100 pelvic radiographs of infants between 90 and 150 days of age. Participants were selected by convenience sampling, based on inclusion criteria. We identified the presence of ONFH and measured biometric parameters, morphology, and anatomical location. Sociodemographic and perinatal data were collected from the participating infants. The prevalence of ONFH was 33%, and the mean age at visualization was 104 days. The presence of ONFH was correlated with birth weight ( = 0.011), discharge weight ( = 0.005), and weight at 1 month ( = 0.034). In our study, female sex ( = 0.004) was associated with a 4.966-fold higher odds of ONFH prevalence compared to males. This study provides relevant evidence regarding the prevalence, morphology, and characteristics of ONFH. Few studies report this information on ONFH in different populations. The optimal timing for radiographic visualization of ONFH in infants remains undefined, but the appearance of the ONFH was concentrated around 104 days of life. The novel association between weight and ONFH provides new insights into DDH. This provides new insights for DDH screening. This association warrants further research for the early detection of DDH.
发育性髋关节发育不良（DDH）影响1% - 3%的新生儿，需要早期检测以获得最佳治疗效果。DDH涉及髋臼与股骨头之间髋臼 - 股骨的异常匹配，这是由髋臼发育浅或股骨头股骨骨化延迟引起的。我们评估了股骨头骨化核（ONFH），以确定其患病率、影像学出现时间以及与围产期因素的关联。我们分析了100例90至150日龄婴儿的骨盆X光片。根据纳入标准，通过便利抽样选择参与者。我们确定了ONFH的存在，并测量了生物测量参数、形态和解剖位置。从参与研究的婴儿中收集了社会人口统计学和围产期数据。ONFH的患病率为33%，可视化的平均年龄为104天。ONFH的存在与出生体重（P = 0.011）、出院体重（P = 0.005）和1个月时的体重（P = 0.034）相关。在我们的研究中，女性（P = 0.004）患ONFH的几率比男性高4.966倍。本研究提供了关于ONFH患病率、形态和特征的相关证据。很少有研究报告不同人群中ONFH的这些信息。婴儿ONFH影像学可视化的最佳时间仍不明确，但ONFH的出现集中在出生后104天左右。体重与ONFH之间的新关联为DDH提供了新的见解。这为DDH筛查提供了新的思路。这种关联值得进一步研究以早期发现DDH。
