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基于超声筛查的连云港市发育性髋关节发育不良的发病率及流行病学特征:一项回顾性研究

Incidence and Epidemiological Characters of Developmental Dysplasia of the Hip in Lianyungang: Based on Ultrasound Screening: A Retrospective Study.

作者信息

Zhu Dongsheng, Zhu Hongqi

机构信息

Department of Pediatric Orthopedics, The First People's Hospital of Lianyungang, Lianyungang, 222000, People's Republic of China.

出版信息

Int J Gen Med. 2022 Dec 13;15:8547-8555. doi: 10.2147/IJGM.S389145. eCollection 2022.

Abstract

OBJECTIVE

To explore the incidence and epidemiological characteristics of developmental dysplasia of hip (DDH) in Lianyungang and provide a basis for early detection, early diagnosis and early treatment.

METHODS

Ultrasound screening was performed on aged 4-6 weeks to collect the incidence and epidemiological profiles of DDH. Graf hip ultrasound imaging was used for screening. DDH was diagnosed with a classification of ≥IIa.

RESULTS

Of the 9803 babies, 4999 were boys and 4687 were girls. There were 117 babies diagnosed with DDH, incidence rate of 1.19%. The incidence of DDH rate at left was higher than that at right (0.89%, 87/9803) vs (0.37%, 36/9803) and the difference was statistically significant (P < 0.001). Multivariate logistic regression analysis indicated that female (OR = 5.059, 95% CI: 3.012-9.109) and first child (OR = 1.871, 95% CI: 1.169-2.832) were the risk factors of DDH. Due to the small number of relevant cases and the absence of DDH cases, improper swaddling, abnormal amniotic fluid volume and confluent malformation could not be included for statistical comparison.

CONCLUSION

The incidence of DDH in infants aged 4-6 weeks in Lianyungang was 1.19% (117/9803). DDH was more prone to occur on the left side. Girl and first-borns were the risk factors of DDH.

摘要

目的

探讨连云港地区发育性髋关节发育不良(DDH)的发病率及流行病学特征,为早期发现、早期诊断和早期治疗提供依据。

方法

对4至6周龄婴儿进行超声筛查,收集DDH的发病率及流行病学资料。采用Graf髋关节超声成像进行筛查。DDH诊断采用≥IIa级分类。

结果

9803例婴儿中,男4999例,女4687例。117例婴儿被诊断为DDH,发病率为1.19%。左侧DDH发病率高于右侧(0.89%,87/9803)对(0.37%,36/9803),差异有统计学意义(P<0.001)。多因素logistic回归分析表明,女性(OR=5.059,95%CI:3.012-9.109)和头胎(OR=1.871,95%CI:1.169-2.832)是DDH的危险因素。因相关病例数少及无DDH病例,襁褓不当、羊水异常及联体畸形未纳入统计比较。

结论

连云港地区4至6周龄婴儿DDH发病率为1.19%(117/9803)。DDH更易发生于左侧。女孩和头胎是DDH的危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee4f/9759016/b64400a12d0e/IJGM-15-8547-g0001.jpg

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