Sung Gipyo, Jang Jieun, Lee Kwan
Pyeongtaek-si Songtan Public Health Center, Pyeongtaek 17730, Republic of Korea.
Department of Preventive Medicine, College of Medicine, Dongguk University, Gyeongju 38067, Republic of Korea.
Children (Basel). 2025 Jul 18;12(7):949. doi: 10.3390/children12070949.
: On 6 June 2023, two varicella cases were reported at a highly vaccinated elementary school in Gyeonggi Province, Republic of Korea. We investigated the outbreak to describe its transmission dynamics; quantify attack rates in school, household, and private-academy settings; and assess the impact of coordinated control measures. : A case-series study included 89 teachers and students who had contact with suspected patients. Using case definitions, laboratory tests, questionnaires, and environmental assessments, we evaluated exposures and factors facilitating spread. : Varicella developed in 23 of 89 contacts (25.8%); laboratory confirmation was obtained in 2 (8.7% of cases). The mean incubation period was 13 days. Epidemic-curve and network analyses indicated that the outbreak began with a single index case and extended through household contacts and private educational facilities, ultimately involving multiple schools. : Breakthrough transmission can occur even when single-dose coverage exceeds 95%, particularly as vaccine-induced immunity may wane over time. Poorly regulated extracurricular facilities, such as private academies, act as bridging hubs that amplify spread across grades and even between schools. For timely detection and control, these venues should be incorporated into routine varicella surveillance, and rapid, coordinated infection-control measures are required across all educational settings.
2023年6月6日，韩国京畿道一所高疫苗接种率的小学报告了两例水痘病例。我们对此次疫情进行了调查，以描述其传播动态；量化学校、家庭和私立学院环境中的发病率；并评估协调控制措施的影响。：一项病例系列研究纳入了89名与疑似患者有接触的教师和学生。通过病例定义、实验室检测、问卷调查和环境评估，我们评估了暴露情况和促进传播的因素。：89名接触者中有23人（25.8%）感染了水痘；2例（占病例的8.7%）获得实验室确诊。平均潜伏期为13天。流行曲线和网络分析表明，此次疫情始于一例索引病例，并通过家庭接触者和私立教育机构传播，最终涉及多所学校。：即使单剂疫苗接种覆盖率超过95%，突破性传播仍可能发生，尤其是随着疫苗诱导的免疫力可能会随着时间减弱。监管不力的课外设施，如私立学院，成为跨年级甚至跨学校传播的桥梁枢纽。为了及时发现和控制疫情，这些场所应纳入常规水痘监测，并且需要在所有教育环境中采取快速、协调的感染控制措施。
