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[对用基因同质株莫斯科-5制备的麻疹活疫苗免疫儿童的临床实验室及血清流行病学检查]

[Clinico-laboratory and seroepidemiological examinations of children immunized with live measles vaccine prepared from genetically homogeneous strain Moscow-5].

作者信息

Unanov S S, Iuminova N V, Pasechnik A L, Sokolova A F, Gordienko N M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1985 Sep(9):49-54.

PMID:4072497
Abstract

The results of the clinico-laboratory and epidemiological study of a newly developed live measles vaccine obtained from strain Moscow-5, genetically homogeneous and cloned from strain JI-16, are presented. The data indicate that the vaccine obtained from strain Moscow-5 is safe and possesses low reactogenicity and high immunological potency, thus meeting all requirements for vaccinal preparations.

摘要

本文介绍了一种新研制的麻疹活疫苗的临床实验室和流行病学研究结果。该疫苗源自莫斯科-5株,基因纯一,是从JI-16株克隆而来。数据表明,源自莫斯科-5株的疫苗安全,反应原性低,免疫效力高,符合疫苗制剂的所有要求。

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