Donnez J, Caprasse J, Casanas-Roux F, Karaman Y, Ferim J, Thomas K
Acta Eur Fertil. 1985 Jul-Aug;16(4):257-61.
Ligation of the proximal and distal ends of the rabbit oviduct was used to induce hydrosalpinges, which shows a remarkable resemblance, both macroscopically and microscopically, to human hydrosalpinges. Isthmic and ampullary biopsies obtained at varying intervals were examined with light microscopy. Progressive deciliation and decrease of epithelial and mucosal fold height were observed in the ampulla, but not in the isthmus. Microstereological study shows progressive reduction of both the number and the relative volume of capillaries in the ampulla. Considering the parallelism of time and localization, it is suggested that epithelial deciliation is caused by vascular disorders.
通过结扎兔输卵管的近端和远端来诱发输卵管积水，其在宏观和微观上都与人类输卵管积水极为相似。在不同时间间隔获取峡部和壶腹部的活检组织，进行光学显微镜检查。在壶腹部观察到纤毛进行性脱落以及上皮和黏膜皱襞高度降低，而在峡部未观察到这种情况。显微立体学研究表明，壶腹部毛细血管的数量和相对体积都在进行性减少。考虑到时间和部位的平行关系，提示上皮纤毛脱落是由血管病变引起的。
