Vasquez G, Oberti C, Boeckx W, Winston R M, Brosens I A
Fertil Steril. 1981 Mar;35(3):342-8.
Damage to fallopian tubes caused by hydrosalpinges is a major reason for persisting infertility. We describe the mucosal changes that occur following induction of experimentally induced hydrosalpinges in 25 rabbits. Ampullary biopsies obtained at varying intervals were examined with light microscopy and scanning and transmission electron microscopy. Mucosal folds showed progressive atrophy. The epithelium was flattened. The population of ciliated cells decreased and, finally, deciliation became generalized. The morphology of nonciliated cells changed from an initial high content of granules of secretion to a final stage of vacuolated cytoplasm. Cell desquamation was common.
输卵管积水所导致的输卵管损伤是持续性不孕的主要原因。我们描述了在25只兔子身上实验性诱导输卵管积水后所发生的黏膜变化。在不同时间间隔获取的壶腹部活检组织用光学显微镜、扫描电子显微镜和透射电子显微镜进行检查。黏膜皱襞呈现进行性萎缩。上皮细胞扁平。纤毛细胞数量减少，最终出现普遍的脱纤毛现象。非纤毛细胞的形态从最初分泌颗粒含量高转变为细胞质空泡化的最终阶段。细胞脱落很常见。
