一种新型锥形尖端鞘系统在胆道癌术前定位活检中的应用
Utility of a novel tapered-tip sheath system for preoperative mapping biopsy of biliary tract cancers.
作者信息
Matsumori Tomoaki, Uza Norimitsu, Okada Kazuhiro, Shiokawa Masahiro, Maruno Takahisa, Nishikawa Yoshihiro, Kuwada Takeshi, Muramoto Yuya, Yasuda Muneji, Yamazaki Hajime, Taura Kojiro, Hatano Etsuro, Kodama Yuzo, Seno Hiroshi
机构信息
Gastroenterology and Hepatology, Kyoto University Hospital, Kyoto City, Japan.
Gastroenterology and Hepatology, Kyoto University, Kyoto, Japan.
出版信息
Endosc Int Open. 2025 Jul 23;13:a26317538. doi: 10.1055/a-2631-7538. eCollection 2025.
BACKGROUND AND STUDY AIMS
Preoperative evaluation of biliary tract cancer progression plays a critical role in assessing resectability and in selecting the appropriate surgical procedure. This study aimed to evaluate the utility of a novel tapered-tip sheath system for mapping biopsy to assess the extent of biliary tract cancer.
PATIENTS AND METHODS
This observational, comparative study included 32 patients who were diagnosed with biliary tract cancers and underwent mapping biopsies with the novel tapered-tip sheath system and 21 patients using the conventional methods before the period. Technical success, total biopsy time, number of biopsy specimens, appropriate tissue sampling, adverse events (AEs), and negative surgical margin in case of surgical resection were evaluated.
RESULTS
The following were the respective results for the novel system and conventional methods groups: technical success rates, 73.3% and 48.4% ( = 0.027); total biopsy times, 11.4 and 23.5 minutes ( = 0.043); median number of specimens obtained per procedure, 6 and 3 ( < 0.001); appropriate tissue sampling rates, 86.1% and 67.2% ( < 0.001); AE rates, 2.1% and 0%; and negative surgical margin rates, 90.4% and 78.6%.
CONCLUSIONS
Preoperative mapping biopsy using the novel tapered-tip sheath system is a promising option for assessing the extent of biliary tract cancers.
背景与研究目的
胆道癌进展的术前评估在评估可切除性和选择合适的手术方式方面起着关键作用。本研究旨在评估一种新型尖锥鞘系统用于测绘活检以评估胆道癌范围的效用。
患者与方法
这项观察性比较研究纳入了32例被诊断为胆道癌并使用新型尖锥鞘系统进行测绘活检的患者，以及21例在此之前使用传统方法的患者。评估了技术成功率、总活检时间、活检标本数量、合适的组织采样情况、不良事件（AE）以及手术切除时切缘阴性情况。
结果
新型系统组和传统方法组的各自结果如下：技术成功率分别为73.3%和48.4%（P = 0.027）；总活检时间分别为11.4分钟和23.5分钟（P = 0.043）；每次操作获得标本的中位数分别为6个和3个（P < 0.001）；合适的组织采样率分别为86.1%和67.2%（P < 0.001）；AE发生率分别为2.1%和0%；切缘阴性率分别为90.4%和78.6%。
结论
使用新型尖锥鞘系统进行术前测绘活检是评估胆道癌范围的一个有前景的选择。
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