Jørgensen P
Acta Psychiatr Scand. 1985 Oct;72(4):364-8. doi: 10.1111/j.1600-0447.1985.tb02622.x.
A study was made of the hospital records of 114 first admission patients under 60 years with a diagnosis of manic-depressive psychosis and coexisting paranoid symptoms. The male/female ratio was 1/1.4, and the females were significantly older. Symptomatology and treatment are presented. Seventy per cent disclosed delusions of reference and misinterpretation and 50% had synthymic delusions. During 11-15 years of admission 75% of the patients were re-admitted. The diagnostic concept was changed in 33%. Significantly more females were diagnosed unipolar manic-depressive. According to the general practitioners and hospital records psychotic traits were still present in 50% of the patients at follow-up. Significantly more patients diagnosed as unipolar manic-depressive had no relapse and no remaining psychotic traits. And significantly more patients with changed diagnosis had remaining psychotic traits. The need for prospective studies of patients with coexisting affective and paranoid symptomatology is stressed.
对114例60岁以下首次入院且诊断为躁郁症合并偏执症状的患者的医院记录进行了研究。男女比例为1/1.4，女性年龄显著更大。文中呈现了症状学和治疗情况。70%的患者表现出关系妄想和错解，50%有情绪协调的妄想。在入院11至15年间，75%的患者再次入院。33%的患者诊断概念发生了改变。被诊断为单相躁郁症的女性显著更多。根据全科医生和医院记录，随访时50%的患者仍存在精神病性特征。被诊断为单相躁郁症的患者复发和残留精神病性特征的显著更少。而诊断改变的患者残留精神病性特征的显著更多。强调了对合并情感和偏执症状的患者进行前瞻性研究的必要性。
