Wang Ellen, Nye Jessica R, Rizvi Imran, Swiekatowski Kylie R, Kahramangil Bora, Won Paul, Kopplin Noa G, Parlamas Stephen F, Trost Jeffrey G, Bhadkamkar Mohin A
From the Division of Plastic and Reconstructive Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX.
Plast Reconstr Surg Glob Open. 2025 Jul 28;13(7):e6995. doi: 10.1097/GOX.0000000000006995. eCollection 2025 Jul.
Although traditional teaching advocates that microsurgical anastomoses should be performed to uninjured vessels outside the zone of injury (ZOI), there is no defined way to assess the extent of the ZOI, and uninjured vessels may not be available. To evaluate the complications ascribed to the ZOI and injured vessels, outcomes between arterial anastomoses fashioned from within the ZOI versus noninjured recipient vessels were compared.
A retrospective review was conducted of adult patients who required lower extremity free flap (FF) reconstruction from 2016 to 2024. Injury to the recipient artery (transection, avulsion, or thrombosis) was determined by intraoperative assessment or preoperative computed tomography angiography. The primary outcome, complications attributed to the arterial anastomosis, was a composite variable defined as return to the operating room during the index hospitalization for arterial thrombosis, partial flap loss, and/or total flap loss.
A total of 285 cases met our inclusion criteria, with 87 (30.5%) FF arterial anastomoses performed to an injured recipient artery. Of the 285 cases in this study, 20 (7.0%) required operating room takeback for arterial thrombosis and/or partial/total flap loss. However, there was no significant difference between the incidence of these complications for FFs anastomosed to injured (6.9%) versus noninjured (7.1%) recipient arteries ( > 0.9).
Although healthy vessels outside the ZOI are preferred for lower extremity reconstruction, the selection of recipient vessels can be guided by surgeon expertise and microsurgical technique when they are unavailable, broadening the options for limb salvage.
尽管传统教学主张应在损伤区域(ZOI)以外对未受伤的血管进行显微外科吻合,但目前尚无明确的方法来评估ZOI的范围,而且可能无法获得未受伤的血管。为了评估归因于ZOI和受伤血管的并发症,比较了在ZOI内进行动脉吻合与使用未受伤的受区血管的手术结果。
对2016年至2024年期间需要进行下肢游离皮瓣(FF)重建的成年患者进行回顾性研究。通过术中评估或术前计算机断层血管造影确定受区动脉损伤(横断、撕脱或血栓形成)。主要结局指标为归因于动脉吻合的并发症,这是一个复合变量,定义为在首次住院期间因动脉血栓形成、部分皮瓣丢失和/或完全皮瓣丢失而返回手术室。
共有285例符合纳入标准,其中87例(30.5%)FF动脉吻合是在受伤的受区动脉上进行的。在本研究的285例病例中,20例(7.0%)因动脉血栓形成和/或部分/完全皮瓣丢失而需要返回手术室。然而,吻合到受伤受区动脉(6.9%)与未受伤受区动脉(7.1%)的FF发生这些并发症的发生率之间无显著差异(>0.9)。
尽管下肢重建首选ZOI以外的健康血管,但在无法获得时,受区血管的选择可由外科医生的专业知识和显微外科技术指导,从而拓宽肢体挽救的选择范围。