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Intraepithelial T cells move from gut to breast to shape lactation.

作者信息

Chawla Amanpreet Singh, Swamy Mahima

机构信息

MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.

出版信息

Nat Immunol. 2025 Aug;26(8):1219-1220. doi: 10.1038/s41590-025-02221-8.

DOI:10.1038/s41590-025-02221-8
PMID:40730898
Abstract
摘要

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本文引用的文献

1
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis.乳腺上皮内淋巴细胞和肠道输入影响泌乳过程中的T细胞动态变化。
Nat Immunol. 2025 Aug;26(8):1411-1422. doi: 10.1038/s41590-025-02218-3. Epub 2025 Jul 29.
2
Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness.乳腺上皮内淋巴细胞促进泌乳及后代健康。
Cell. 2025 Mar 20;188(6):1662-1680.e24. doi: 10.1016/j.cell.2025.01.028. Epub 2025 Feb 14.
3
Human breastmilk memory T cells throughout lactation manifest activated tissue-oriented profile with prominent regulation.
人乳记忆 T 细胞在整个哺乳期表现出激活的组织定向表型，并具有显著的调节作用。
JCI Insight. 2024 Sep 3;9(20):e181788. doi: 10.1172/jci.insight.181788.
4
Association of reproductive risk factors and breast cancer molecular subtypes: a systematic review and meta-analysis.生殖风险因素与乳腺癌分子亚型的关联：系统评价和荟萃分析。
BMC Cancer. 2023 Jul 10;23(1):644. doi: 10.1186/s12885-023-11049-0.
5
Programme of self-reactive innate-like T cell-mediated cancer immunity.自我反应性先天样 T 细胞介导的癌症免疫计划。
Nature. 2022 May;605(7908):139-145. doi: 10.1038/s41586-022-04632-1. Epub 2022 Apr 20.
6
Mechanisms of activation of innate-like intraepithelial T lymphocytes.固有样上皮内 T 淋巴细胞的激活机制。
Mucosal Immunol. 2020 Sep;13(5):721-731. doi: 10.1038/s41385-020-0294-6. Epub 2020 May 15.
7
Benefits of Lactoferrin, Osteopontin and Milk Fat Globule Membranes for Infants.乳铁蛋白、骨桥蛋白和乳脂肪球膜对婴儿的益处。
Nutrients. 2017 Jul 28;9(8):817. doi: 10.3390/nu9080817.
8
Transfer of Maternal Immune Cells by Breastfeeding: Maternal Cytotoxic T Lymphocytes Present in Breast Milk Localize in the Peyer's Patches of the Nursed Infant.母乳喂养传递母体免疫细胞：母乳中存在的母体细胞毒性T淋巴细胞定位于哺乳婴儿的派尔集合淋巴结。
PLoS One. 2016 Jun 10;11(6):e0156762. doi: 10.1371/journal.pone.0156762. eCollection 2016.