Liu Hao, Qin Yao, Hu Yuan-Yuan, Zhang Ling, Zhang Xin-Yu, Xie Jieyu, Chen Shu-Ting, Liu Jia-Fan, Li Lixia
School of Animal Science and Technology, Foshan University, 528225, Foshan, Guangdong, China.
Arch Virol. 2025 Jul 29;170(8):184. doi: 10.1007/s00705-025-06371-w.
In this study, we analyzed 137 liver samples collected from deceased Muscovy ducks in Guangdong, China, between 2020 and 2023. The Muscovy duck parvovirus (MDPV) strain GD2407 was isolated from these samples, and its genome sequence was determined. The genome of MDVP strain GD2407 is 5067 nt in length, encoding both non-structural and structural proteins, and its genome sequence is 99.9% identical to that of strain GDZJ1901. Recombination analysis suggested that strain GD2407 originated from a recombination event between MDPV and goose parvovirus (GPV). Phylogenetic analysis showed that strain GD2407 is genetically closely related to strain GDZJ1901 but distinct from strain GD201911, which was prevalent before 2020. These findings suggest that the circulation of MDPV in this region may contribute to illness and mortality in ducks.
在本研究中，我们分析了2020年至2023年间从中国广东死亡的番鸭身上采集的137份肝脏样本。从这些样本中分离出番鸭细小病毒（MDPV）毒株GD2407，并测定了其基因组序列。MDPV毒株GD2407的基因组长度为5067个核苷酸，编码非结构蛋白和结构蛋白，其基因组序列与毒株GDZJ1901的序列一致性为99.9%。重组分析表明，毒株GD2407起源于MDPV和鹅细小病毒（GPV）之间的重组事件。系统发育分析表明，毒株GD2407在遗传上与毒株GDZJ1901密切相关，但与2020年之前流行的毒株GD201911不同。这些发现表明，该地区MDPV的传播可能导致鸭群发病和死亡。
