de Paula Marcelo Silva, de Oliveira Sheyla Mara Silva, Quaresma Tatiane Costa, Conde Guilherme Augusto Barros, Nogueira Laura Maria Vidal, Conde Valney Mara Gomes, de Souza Adjanny Estela Santos, Moraes Waldiney Pires, Moraes Camila Castilho, Honorato Marcos Manoel, Marinho Daliane Ferreira, de Paula Fernandes Franciane, de Aguiar Valentim Lívia
Academic of the State University of Pará- UEPA, Santarém, Pará, Brasil.
State University of Pará - UEPA, Santarém, Pará, Brasil.
BMC Infect Dis. 2025 Jul 29;25(1):954. doi: 10.1186/s12879-025-11327-1.
This study investigated the impact of post-COVID-19 syndrome on the quality of life, mental health, and functional capacity of individuals from ethnically diverse and socioeconomically vulnerable populations in the Brazilian Amazon. The sample consisted of 25 clinically diagnosed individuals from remote communities, predominantly women (60%) and racially diverse, including mixed-race (56%), Indigenous (32%), Black (8%), and White (4%) participants. Validated instruments were used to assess fatigue, anxiety, depression, quality of life, and physical performance. The findings revealed high rates of moderate to extreme fatigue (88%) and psychological symptoms, with over half of participants showing signs of anxiety or depression. Functional impairment was confirmed through the 1-Minute Sit-to-Stand Test. Correlation analyses showed that older age, lower education, and lower income were associated with worse mental health and quality of life outcomes. Cluster and principal component analyses identified distinct symptomatic and sociodemographic profiles, with the most disadvantaged groups presenting the greatest burden. These results highlight the disproportionate effects of post-COVID-19 syndrome on vulnerable populations and emphasize the need for comprehensive public health interventions that integrate physical, mental, and social care dimensions.
本研究调查了新冠后综合征对巴西亚马逊地区不同种族和社会经济弱势群体个体的生活质量、心理健康和功能能力的影响。样本包括25名来自偏远社区的临床诊断个体，主要为女性（60%），种族多样，包括混血（56%）、原住民（32%）、黑人（8%）和白人（4%）参与者。使用经过验证的工具来评估疲劳、焦虑、抑郁、生活质量和身体表现。研究结果显示，中度至极度疲劳（88%）和心理症状的发生率很高，超过一半的参与者表现出焦虑或抑郁迹象。通过1分钟坐立试验证实了功能损害。相关分析表明，年龄较大、教育程度较低和收入较低与较差的心理健康和生活质量结果相关。聚类分析和主成分分析确定了不同的症状和社会人口学特征，最弱势群体负担最重。这些结果凸显了新冠后综合征对弱势群体的不成比例影响，并强调需要综合的公共卫生干预措施，将身体、心理和社会护理层面整合起来。
