. Serviço de Pneumologia, Centro Hospitalar Universitário do Porto, Porto, Portugal.
. Serviço de Pneumologia, Instituto de Ciências Biomédicas Abel Salazar, Porto, Portugal.
J Bras Pneumol. 2023 May 26;49(3):e20230027. doi: 10.36416/1806-3756/e20230027. eCollection 2023.
To analyze the relationship between one-minute sit-to-stand test (1MSTST) parameters and a diagnosis of post COVID-19 condition in a cohort of patients who previously had COVID-19.
This was a prospective cohort study of patients with post COVID-19 condition referred for body plethysmography at a tertiary university hospital. Post COVID-19 condition was defined in accordance with the current WHO criteria.
Fifty-three patients were analyzed. Of those, 25 (47.2%) met the clinical criteria for post COVID-19 condition. HR was lower in the patients with post COVID-19 condition than in those without it at 30 s after initiation of the 1MSTST (86.2 ± 14.3 bpm vs. 101.2 ± 14.7 bpm; p < 0.001) and at the end of the test (94.4 ± 18.2 bpm vs. 117.3 ± 15.3 bpm; p < 0.001). The ratio between HR at the end of the 1MSTST and age-predicted maximal HR (HRend/HRmax) was lower in the group of patients with post COVID-19 condition (p < 0.001). An HRend/HRmax of < 62.65% showed a sensitivity of 78.6% and a specificity of 82.0% for post COVID-19 condition. Mean SpO2 at the end of the 1MSTST was lower in the patients with post COVID-19 condition than in those without it (94.9 ± 3.6% vs. 96.8 ± 2.4%; p = 0.030). The former group of patients did fewer repetitions on the 1MSTST than did the latter (p = 0.020).
Lower SpO2 and HR at the end of the 1MSTST, as well as lower HR at 30 s after initiation of the test, were associated with post COVID-19 condition. In the appropriate clinical setting, an HRend/HRmax of < 62.65% should raise awareness for the possibility of post COVID-19 condition.
分析一分钟坐立试验（1MSTST）参数与既往感染 COVID-19 患者新冠后状况诊断之间的关系。
这是一项在一家三级大学医院进行的针对新冠后状况患者进行体描记法检查的前瞻性队列研究。新冠后状况的定义符合当前世界卫生组织的标准。
共分析了 53 名患者。其中，25 名（47.2%）符合新冠后状况的临床标准。与无新冠后状况的患者相比，新冠后状况患者在 1MSTST 开始后 30 秒（86.2±14.3 bpm 与 101.2±14.7 bpm；p<0.001）和试验结束时（94.4±18.2 bpm 与 117.3±15.3 bpm；p<0.001）的心率较低。1MSTST 结束时的心率与年龄预测最大心率（HRend/HRmax）的比值在新冠后状况组较低（p<0.001）。HRend/HRmax<62.65%对新冠后状况的敏感性为 78.6%，特异性为 82.0%。新冠后状况患者在 1MSTST 结束时的平均 SpO2 低于无新冠后状况的患者（94.9±3.6%与 96.8±2.4%；p=0.030）。前者组在 1MSTST 上的重复次数少于后者（p=0.020）。
1MSTST 结束时较低的 SpO2 和 HR，以及试验开始后 30 秒时较低的 HR，与新冠后状况有关。在适当的临床环境中，HRend/HRmax<62.65%应引起对新冠后状况可能性的关注。
