Serin Yeliz, Andruškienė Jurgita, Verma Anil K, Śmiełowska Monika, Dzingelevičius Nerijus, Vilčiauskis Albinas, Vaičekauskaitė Rita, Bradauskienė Vijolė, Buszewski Bogusław, Dzingelevičienė Reda
Department of Nutrition and Dietetics, Faculty of Health Sciences, Cukurova University, Adana 01330, Türkiye.
Faculty of Health Science, Klaipeda University, H. Manto Str. 84, 92294 Klaipeda, Lithuania.
Medicina (Kaunas). 2025 Jul 16;61(7):1278. doi: 10.3390/medicina61071278.
: Celiac disease (CD) is a common gluten-related disorder associated with significantly worsened quality of life. The aim of this pilot study was to evaluate the quality of life of adult celiac patients living in Lithuania and their compliance with a gluten-free diet. : This cross-sectional study was conducted on individuals aged 18 to 75 years diagnosed with CD and residing within the borders of Lithuania. This pilot study involved 73 participants, comprising 68 females and 5 males. The CD Specific Quality of Life Scale (CD-QOL) consisted of 20 items across four sub-dimensions. Responses to scale items were graded with a score ranging from 1 (not at all) to 5 (very much). The total score obtained from the scale can range up to 100, with a score < 40 classified as poor, 40-50 as moderate, and > 50 as good quality of life. Additionally, ten questions related to gluten-free diet-related quality of life were used. : The mean age of diagnosis for females (32.6 ± 11.7) was higher than that for males (22.0 ± 12.1), < 0.05. The mean self-reported BMI for males (25.8 ± 4.5) was higher than that for females (22.3 ± 5.2), < 0.05. The mean quality-of-life score (66.4 ± 12.5) was significantly higher in the good quality-of-life group compared to the poor group (33.7 ± 3.9), < 0.001. Half of the respondents (50.7%) reported that gluten-free products are expensive, and 45.2% confirmed difficulties in dining out on a gluten-free diet. : The results of this pilot study indicate that CD is associated with a worsened quality of life and that compliance with a gluten-free diet is primarily influenced by economic factors, such as the high cost of the diet.
乳糜泻（CD）是一种常见的麸质相关疾病，会显著降低生活质量。这项初步研究的目的是评估立陶宛成年乳糜泻患者的生活质量及其对无麸质饮食的依从性。
这项横断面研究针对的是年龄在18至75岁之间、被诊断患有CD且居住在立陶宛境内的个体。这项初步研究涉及73名参与者，其中包括68名女性和5名男性。乳糜泻特定生活质量量表（CD-QOL）由四个子维度的20个项目组成。对量表项目的回答按1（一点也不）至5（非常）进行评分。量表的总分最高可达100分，得分<40分为差，40 - 50分为中等，>50分为生活质量良好。此外，还使用了十个与无麸质饮食相关生活质量的问题。
女性的平均诊断年龄（32.6±11.7）高于男性（22.0±12.1），P<0.05。男性自我报告的平均体重指数（25.8±4.5）高于女性（22.3±5.2），P<0.05。生活质量良好组的平均生活质量得分（66.4±12.5）显著高于差组（33.7±3.9），P<0.001。一半的受访者（50.7%）表示无麸质产品价格昂贵，45.2%的受访者确认在外出就餐时遵循无麸质饮食存在困难。
这项初步研究的结果表明，CD与生活质量下降有关，并且对无麸质饮食的依从性主要受经济因素影响，例如饮食成本高昂。
