Donate or Not to Donate-Willingness to Donate and Accept Donor Human Milk.

: Breast milk donation is increasingly recognized as a vital public health resource, providing optimal nutrition for infants who cannot be breastfed by their biological mothers. Human milk banks play a crucial role in supporting infant health, particularly for preterm and medically vulnerable infants. Despite its recognized benefits, the practice of breast milk donation and utilization remains influenced by a complex interplay of individual, social, and cultural factors. : This study systematically examines how demographic and sociocultural variables are associated with attitudes and behaviors related to breast milk donation. Data were collected from 1223 Israeli mothers via questionnaires distributed through WhatsApp groups between April and May 2025. By analyzing the questionnaire results, the research identified key predictors of willingness to donate and use donated milk, as well as patterns of awareness and perceived support within different population groups. : Higher education ( = 12.87, = 0.0016) and settlement type ( = 83.096, = 0.000) were significantly associated with greater willingness to donate breast milk. Income level had no effect on donation behavior, though higher-income participants were more open to its use (χ = 86.838, = 0.000). Lifestyle also influenced perceptions of social support ((2, 1220) = 259.4036, < 0.001) and cultural support ((2, 1220) = 601.2383, < 0.001) of milk donation and use. Significant correlation was found between perceived cultural and social support ( = 5.140, = 0.000), emphasizing their interrelated influence on milk donation attitudes. : The findings assist in guiding the development of public health policies, as well as targeted awareness campaigns, to promote equitable access to donor milk services across varied communities. From the public health perspective, the findings of this study can orientate campaigns that encourage both donation and use of breast milk focusing on segments of the population in which the level of awareness is relatively low.