Bragg L E, Thompson J S, Burnett D A, Hodgson P E, Rikkers L F
Am J Surg. 1985 Dec;150(6):694-7. doi: 10.1016/0002-9610(85)90411-8.
The incidence and significance of pancreas-related complications (pseudocysts, abscesses, and fistulas) were evaluated in 100 patients with acute pancreatitis. Alcoholic (40 percent), biliary (20 percent), and postoperative (15 percent) pancreatitis were seen most frequently. Eighteen patients had severe pancreatitis (3 or more Ranson's criteria). The overall mortality rate was 8 percent, and there were 16 pancreas-related complications. Pancreas-related complications developed in eight patients (53 percent), including two pseudocysts, four abscesses, and two fistulas. The incidence of pancreas-related complications was significantly greater in the postoperative group than in the overall 9 percent incidence in the other groups (p less than 0.005). Half of these patients required operation for their complications. Patients with postoperative pancreatitis are at a markedly increased risk of pancreas-related complications. Since these complications occur even in apparently mild cases of pancreatitis, these patients should be followed closely to detect pancreas-related complications.
对100例急性胰腺炎患者评估胰腺相关并发症(假性囊肿、脓肿和瘘管)的发生率及意义。最常见的病因是酒精性胰腺炎(40%)、胆源性胰腺炎(20%)和术后胰腺炎(15%)。18例患者为重症胰腺炎(符合3项或更多项兰森标准)。总死亡率为8%,有16例胰腺相关并发症。8例患者(53%)发生胰腺相关并发症,包括2例假性囊肿、4例脓肿和2例瘘管。术后组胰腺相关并发症的发生率显著高于其他组9%的总体发生率(p<0.005)。这些患者中有一半因并发症需要手术治疗。术后胰腺炎患者发生胰腺相关并发症的风险显著增加。由于这些并发症甚至在看似轻度的胰腺炎病例中也会出现,因此应对这些患者密切随访以发现胰腺相关并发症。