Oladeji Olajide O, Ogah Okechukwu S, Olunuga Taiwo O, Durodola Amina, Adebayo Saheed O, Aje Akinyemi, Nwamadiegesi Caroline A, Ezeh Chidera H, Adeyeye Oluwabunmi V, Obiekwe Franklin E, Eziechina Collins C, Digwu Shalom O, Akinosi Taiwo M, Abhulimen Enahoro S, Ogah Chidinma M, Odenigbo Miracle N, Aniekan Etim U
Cardiology Unit, Department of Medicine, Federal Medical Centre, Abeokuta, Nigeria.
Cardiology Unit, Department of Medicine, University of Ibadan, Ibadan, Nigeria.
Heart Rhythm O2. 2025 Apr 24;6(7):1020-1027. doi: 10.1016/j.hroo.2025.04.006. eCollection 2025 Jul.
Atrial fibrillation (AF) is the most common sustained cardiac dysrhythmia seen in clinical practice that requires treatment. Data on the burden of AF in patients with heart failure (HF) are generally lacking in Nigeria and Africa.
This study aimed to characterize the clinical and echocardiographic profiles of patients with AF in our clinical practice.
An observational hospital-based study was conducted on patients with AF in the setting of HF seen at an urban tertiary hospital in Nigeria over 9 months. All patients had both clinical and echocardiographic evaluations.
A total of 100 cases of AF in HF were recruited for the study. Of these, 54 were men and 46 women. The mean age of the participants was 55.7 (13.3) years (male: 58.8 [10.5], female: 52.1 [15.4] years). The age range was 18 to 86 years for the cohort (male: 32-86 years, female: 18-79 years). Most participants were older than 40 years (88%). Hypertensive heart disease was the most common risk factor, although rheumatic heart disease and thyroid heart disease played a major role in women and most required anticoagulation.
AF in HF in our setting occurred at a younger age compared with data from Western Europe and North America. Women were diagnosed at a younger age because of the risk factors. Hypertensive heart disease was the most common risk factor, and most patients required anticoagulation. Studies are needed to determine the impact of AF on the outcome of HF in our setting.
心房颤动（AF）是临床实践中最常见的需要治疗的持续性心律失常。在尼日利亚和非洲，心力衰竭（HF）患者中AF负担的数据普遍缺乏。
本研究旨在描述我们临床实践中AF患者的临床和超声心动图特征。
在尼日利亚一家城市三级医院对9个月内就诊的HF合并AF患者进行了一项基于医院的观察性研究。所有患者均进行了临床和超声心动图评估。
本研究共纳入100例HF合并AF患者。其中，男性54例，女性46例。参与者的平均年龄为55.7（13.3）岁（男性：58.8 [10.5]岁，女性：52.1 [15.4]岁）。该队列的年龄范围为18至86岁（男性：32 - 86岁，女性：18 - 79岁）。大多数参与者年龄超过40岁（88%）。高血压性心脏病是最常见的危险因素，尽管风湿性心脏病和甲状腺性心脏病在女性中起主要作用，且大多数需要抗凝治疗。
与西欧和北美的数据相比，我们研究中的HF合并AF发生年龄较轻。由于危险因素，女性被诊断出AF的年龄更小。高血压性心脏病是最常见的危险因素，且大多数患者需要抗凝治疗。需要开展研究以确定AF对我们研究环境中HF结局的影响。
